Deep crypt secretory cells shape region-specific mucin glycosylation patterns in the mouse colon.

The colonic mucin layer, comprising highly glycosylated mucin proteins, is crucial for maintaining colonic health. Its region-specific glycosylation patterns are indispensable for adapting to distinct physiological and microbial environments along the colon, thus ensuring appropriate mucin layer fun...

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Bibliographic Details
Main Authors: Daisuke Sugahara, Hayato Kawakami, Yoshihiro Akimoto
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2025-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0326157
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