A Community Effort to Develop Common Data Elements for Pre-Clinical Spinal Cord Injury Research

For nearly 350 years, the process of disseminating scientific knowledge has remained largely unchanged. Scientists conduct experiments, analyze the data, and publish their findings in the form of scientific articles. Since the turn of the century, this process has been challenged by numerous open sc...

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Main Authors: Britt A. Fedor, Abel Torres-Espin, Romana Vavrek, Maryann E. Martone, John L. Bixby, John C. Gensel, Vance Lemmon, Jeffrey S. Grethe, J. Russel Huie, Adam R. Ferguson, Karim Fouad, Collaboration group
Format: Article
Language:English
Published: Mary Ann Liebert 2025-04-01
Series:Neurotrauma Reports
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Online Access:https://www.liebertpub.com/doi/full/10.1089/NEUR.2025.0021
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author Britt A. Fedor
Abel Torres-Espin
Romana Vavrek
Maryann E. Martone
John L. Bixby
John C. Gensel
Vance Lemmon
Jeffrey S. Grethe
J. Russel Huie
Adam R. Ferguson
Karim Fouad
Collaboration group
Collaboration group
author_facet Britt A. Fedor
Abel Torres-Espin
Romana Vavrek
Maryann E. Martone
John L. Bixby
John C. Gensel
Vance Lemmon
Jeffrey S. Grethe
J. Russel Huie
Adam R. Ferguson
Karim Fouad
Collaboration group
Collaboration group
author_sort Britt A. Fedor
collection DOAJ
description For nearly 350 years, the process of disseminating scientific knowledge has remained largely unchanged. Scientists conduct experiments, analyze the data, and publish their findings in the form of scientific articles. Since the turn of the century, this process has been challenged by numerous open science and data sharing efforts to enhance transparency, reproducibility, and replicability of scientific research. Big data approaches, together with machine learning and artificial intelligence, are frequently used to gain insight into the ever-growing complexity of biological systems and biomedical research. To utilize these approaches and harness the continuously increasing computational power requires data to be both machine readable and, ideally, harmonized across studies. Therein lies the challenge: understanding how to organize and describe data is a critical skill for scientists, yet one that is rarely explicitly taught. Common data elements (CDEs), standardized definitions, and reporting structures for data represent a practical solution to this challenge. With the goal of creating a common language to describe and share pre-clinical spinal cord injury (SCI) research data, the open data commons for SCI, in collaboration with the National Institute of Neurological Disorders and Stroke, kicked off this process with the “Preclinical SCI Common Data Elements (CDE) Workshop,” held in conjunction with the National Neurotrauma Symposium in San Francisco, California in June 2024. In this report, we discuss the workshop proceedings, summarize the input provided by the SCI research community, share insights from related CDE efforts, and provide a pragmatic approach to creating CDEs for pre-clinical SCI research.
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spelling doaj-art-18868d492af842278a71752779ba2e0d2025-08-20T03:19:07ZengMary Ann LiebertNeurotrauma Reports2689-288X2025-04-016139140110.1089/NEUR.2025.0021A Community Effort to Develop Common Data Elements for Pre-Clinical Spinal Cord Injury ResearchBritt A. FedorAbel Torres-EspinRomana VavrekMaryann E. MartoneJohn L. BixbyJohn C. GenselVance LemmonJeffrey S. GretheJ. Russel HuieAdam R. FergusonKarim FouadCollaboration groupCollaboration group0The Preclinical SCI Common Data Elements (CDE) Workshop ParticipantsFor nearly 350 years, the process of disseminating scientific knowledge has remained largely unchanged. Scientists conduct experiments, analyze the data, and publish their findings in the form of scientific articles. Since the turn of the century, this process has been challenged by numerous open science and data sharing efforts to enhance transparency, reproducibility, and replicability of scientific research. Big data approaches, together with machine learning and artificial intelligence, are frequently used to gain insight into the ever-growing complexity of biological systems and biomedical research. To utilize these approaches and harness the continuously increasing computational power requires data to be both machine readable and, ideally, harmonized across studies. Therein lies the challenge: understanding how to organize and describe data is a critical skill for scientists, yet one that is rarely explicitly taught. Common data elements (CDEs), standardized definitions, and reporting structures for data represent a practical solution to this challenge. With the goal of creating a common language to describe and share pre-clinical spinal cord injury (SCI) research data, the open data commons for SCI, in collaboration with the National Institute of Neurological Disorders and Stroke, kicked off this process with the “Preclinical SCI Common Data Elements (CDE) Workshop,” held in conjunction with the National Neurotrauma Symposium in San Francisco, California in June 2024. In this report, we discuss the workshop proceedings, summarize the input provided by the SCI research community, share insights from related CDE efforts, and provide a pragmatic approach to creating CDEs for pre-clinical SCI research.https://www.liebertpub.com/doi/full/10.1089/NEUR.2025.0021common data elementsdata managementdata sharingneurotraumaODC-SCIspinal cord injury
spellingShingle Britt A. Fedor
Abel Torres-Espin
Romana Vavrek
Maryann E. Martone
John L. Bixby
John C. Gensel
Vance Lemmon
Jeffrey S. Grethe
J. Russel Huie
Adam R. Ferguson
Karim Fouad
Collaboration group
Collaboration group
A Community Effort to Develop Common Data Elements for Pre-Clinical Spinal Cord Injury Research
Neurotrauma Reports
common data elements
data management
data sharing
neurotrauma
ODC-SCI
spinal cord injury
title A Community Effort to Develop Common Data Elements for Pre-Clinical Spinal Cord Injury Research
title_full A Community Effort to Develop Common Data Elements for Pre-Clinical Spinal Cord Injury Research
title_fullStr A Community Effort to Develop Common Data Elements for Pre-Clinical Spinal Cord Injury Research
title_full_unstemmed A Community Effort to Develop Common Data Elements for Pre-Clinical Spinal Cord Injury Research
title_short A Community Effort to Develop Common Data Elements for Pre-Clinical Spinal Cord Injury Research
title_sort community effort to develop common data elements for pre clinical spinal cord injury research
topic common data elements
data management
data sharing
neurotrauma
ODC-SCI
spinal cord injury
url https://www.liebertpub.com/doi/full/10.1089/NEUR.2025.0021
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