Use of port-a-cath in cancer patients: a single-center experience
Introduction: Central venous catheters play an important role in the management of cancer patients. Different types of devices are associated with different patterns of complications. We report on the pattern of use and rate of complications of port-a-caths in patients diagnosed with malignant cance...
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| Language: | English |
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The Journal of Infection in Developing Countries
2014-11-01
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| Series: | Journal of Infection in Developing Countries |
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| Online Access: | https://jidc.org/index.php/journal/article/view/4155 |
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| author | Philomena Charlotte D’Souza Shiyam Kumar Annupam Kakaria Rashid Al-Sukaiti Khawaja Farhan Zahid Muhammad Furrukh Ikram A Burney Mansour S Al-Moundhri |
| author_facet | Philomena Charlotte D’Souza Shiyam Kumar Annupam Kakaria Rashid Al-Sukaiti Khawaja Farhan Zahid Muhammad Furrukh Ikram A Burney Mansour S Al-Moundhri |
| author_sort | Philomena Charlotte D’Souza |
| collection | DOAJ |
| description | Introduction: Central venous catheters play an important role in the management of cancer patients. Different types of devices are associated with different patterns of complications. We report on the pattern of use and rate of complications of port-a-caths in patients diagnosed with malignant cancer at a single institution.
Methodology: The data were collected retrospectively from patients who received the treatment for solid tumors or lymphoma through a port-a-cath at the Sultan Qaboos University Hospital (SQUH) between January 2007 and February 2013.
Results: A total of 117 port-a-caths were inserted in 106 patients. The majority (86; 73.5%) were implanted by an interventional radiologist, and the right internal jugular vein was accessed in 79 (67.5%) patients. Mean catheter indwelling time was 354 (range 3–1,876) days for all patients, 252 (3–1,876) and 389 days (13–1,139) for patients with and without complications, respectively. Thirty (25.6%) port-a-caths were removed prematurely, mainly due to infectious complications, while 17 (14.5%) were removed after completion of treatment. Staphylococcus aureus was the most frequently isolated organism, found in 8 (6.8%) patients. Underlying diagnosis (p < 0.001), chemotherapy regimen (p < 0.001), sensitivity to antibiotics (p = 0.01), and any complication (p < 0.001) were significant factors affecting the duration of port-a-cath use. None of these factors were significant on multivariate cox regression analysis.
Conclusions: The mean duration of port-a-cath use was almost one year. Infection was the most common complication leading to premature removal, followed by port thrombosis.
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| format | Article |
| id | doaj-art-188686e3589f4b0b896d15ad94f9c6f8 |
| institution | OA Journals |
| issn | 1972-2680 |
| language | English |
| publishDate | 2014-11-01 |
| publisher | The Journal of Infection in Developing Countries |
| record_format | Article |
| series | Journal of Infection in Developing Countries |
| spelling | doaj-art-188686e3589f4b0b896d15ad94f9c6f82025-08-20T02:27:23ZengThe Journal of Infection in Developing CountriesJournal of Infection in Developing Countries1972-26802014-11-0181110.3855/jidc.4155Use of port-a-cath in cancer patients: a single-center experiencePhilomena Charlotte D’Souza0Shiyam Kumar1Annupam Kakaria2Rashid Al-Sukaiti3Khawaja Farhan Zahid4Muhammad Furrukh5Ikram A Burney6Mansour S Al-Moundhri7Sultan Qaboos University Hospital, Muscat, OmanSultan Qaboos University Hospital, Muscat, OmanSultan Qaboos University Hospital, Muscat, OmanSultan Qaboos University Hospital, Muscat, OmanSultan Qaboos University Hospital, Muscat, OmanSultan Qaboos University Hospital, Muscat, OmanSultan Qaboos University Hospital, Muscat, OmanSultan Qaboos University Hospital, Muscat, OmanIntroduction: Central venous catheters play an important role in the management of cancer patients. Different types of devices are associated with different patterns of complications. We report on the pattern of use and rate of complications of port-a-caths in patients diagnosed with malignant cancer at a single institution. Methodology: The data were collected retrospectively from patients who received the treatment for solid tumors or lymphoma through a port-a-cath at the Sultan Qaboos University Hospital (SQUH) between January 2007 and February 2013. Results: A total of 117 port-a-caths were inserted in 106 patients. The majority (86; 73.5%) were implanted by an interventional radiologist, and the right internal jugular vein was accessed in 79 (67.5%) patients. Mean catheter indwelling time was 354 (range 3–1,876) days for all patients, 252 (3–1,876) and 389 days (13–1,139) for patients with and without complications, respectively. Thirty (25.6%) port-a-caths were removed prematurely, mainly due to infectious complications, while 17 (14.5%) were removed after completion of treatment. Staphylococcus aureus was the most frequently isolated organism, found in 8 (6.8%) patients. Underlying diagnosis (p < 0.001), chemotherapy regimen (p < 0.001), sensitivity to antibiotics (p = 0.01), and any complication (p < 0.001) were significant factors affecting the duration of port-a-cath use. None of these factors were significant on multivariate cox regression analysis. Conclusions: The mean duration of port-a-cath use was almost one year. Infection was the most common complication leading to premature removal, followed by port thrombosis. https://jidc.org/index.php/journal/article/view/4155port-a-cathchemotherapyinfectioncancerOman |
| spellingShingle | Philomena Charlotte D’Souza Shiyam Kumar Annupam Kakaria Rashid Al-Sukaiti Khawaja Farhan Zahid Muhammad Furrukh Ikram A Burney Mansour S Al-Moundhri Use of port-a-cath in cancer patients: a single-center experience Journal of Infection in Developing Countries port-a-cath chemotherapy infection cancer Oman |
| title | Use of port-a-cath in cancer patients: a single-center experience |
| title_full | Use of port-a-cath in cancer patients: a single-center experience |
| title_fullStr | Use of port-a-cath in cancer patients: a single-center experience |
| title_full_unstemmed | Use of port-a-cath in cancer patients: a single-center experience |
| title_short | Use of port-a-cath in cancer patients: a single-center experience |
| title_sort | use of port a cath in cancer patients a single center experience |
| topic | port-a-cath chemotherapy infection cancer Oman |
| url | https://jidc.org/index.php/journal/article/view/4155 |
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