Non-pharmacological Approaches to Treatment of Patients over 60 Years as a Way to Improve Pharmacotherapy Safety and Prevent Polypharmacy

Abstract. The demographic aging of the population of the earth observed in recent years is associated, inter alia, with the advent of new effective and safe medicines. However, the availability of highly effective drugs on the market also has a reverse side — the appearance of adverse drug reactions...

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Main Authors: A. P. Pereverzev, O. N. Tkacheva, Yu. V. Kotovskaya, Yu. S. Onuchina, E. N. Dudinskaya, A. V. Naumov
Format: Article
Language:Russian
Published: Ministry of Health of the Russian Federation, Federal State Budgetary Institution «Scientific Centre for Expert Evaluation of Medicinal Products» 2018-12-01
Series:Безопасность и риск фармакотерапии
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Online Access:https://www.risksafety.ru/jour/article/view/129
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author A. P. Pereverzev
O. N. Tkacheva
Yu. V. Kotovskaya
Yu. S. Onuchina
E. N. Dudinskaya
A. V. Naumov
author_facet A. P. Pereverzev
O. N. Tkacheva
Yu. V. Kotovskaya
Yu. S. Onuchina
E. N. Dudinskaya
A. V. Naumov
author_sort A. P. Pereverzev
collection DOAJ
description Abstract. The demographic aging of the population of the earth observed in recent years is associated, inter alia, with the advent of new effective and safe medicines. However, the availability of highly effective drugs on the market also has a reverse side — the appearance of adverse drug reactions (ADRs), in particular as a result of drug-drug interactions. The use of non-pharmacological methods of treatment and prevention of diseases seems particularly relevant for patients of the older age group, as it allows not only to reduce the drug burden, to reduce the risk of ADRs but also to improve the patient’s state in case of diseases that have no effective pharmacotherapy and pharmacological prophylaxis. The aim of the study was to systematize and analyze data on non-pharmacological treatment methods in order to increase the safety of pharmacotherapy and prevent polypragmasia in elderly patients by informing health care providers about non-drug methods of correcting significant geriatric problems. The approaches to the correction of some major geriatric problems (delirium, sarcopenia, pain syndrome), including cognitive training, physical activity, diet, frequent reorientation of patients, placement of patients in specially equipped rooms («delirium room») were presented. The use of non-pharmacological approaches can significantly improve the safety of drug therapy, reduce the risks of ADRs, improve the patient’s prognosis and quality of life, and also effectively prevent polypharmacy.
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institution Kabale University
issn 2312-7821
2619-1164
language Russian
publishDate 2018-12-01
publisher Ministry of Health of the Russian Federation, Federal State Budgetary Institution «Scientific Centre for Expert Evaluation of Medicinal Products»
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spelling doaj-art-1884762c87f148088d0501d6b0efccfb2025-08-20T03:43:01ZrusMinistry of Health of the Russian Federation, Federal State Budgetary Institution «Scientific Centre for Expert Evaluation of Medicinal Products»Безопасность и риск фармакотерапии2312-78212619-11642018-12-016417417910.30895/2312-7821-2018-6-4-174-179118Non-pharmacological Approaches to Treatment of Patients over 60 Years as a Way to Improve Pharmacotherapy Safety and Prevent PolypharmacyA. P. Pereverzev0O. N. Tkacheva1Yu. V. Kotovskaya2Yu. S. Onuchina3E. N. Dudinskaya4A. V. Naumov5Pirogov Russian National Research Medical University of the Ministry of Health of the Russian Federation, Russian Clinical and Research Center of Gerontology, MoscowPirogov Russian National Research Medical University of the Ministry of Health of the Russian Federation, Russian Clinical and Research Center of Gerontology, MoscowPirogov Russian National Research Medical University of the Ministry of Health of the Russian Federation, Russian Clinical and Research Center of Gerontology, MoscowPirogov Russian National Research Medical University of the Ministry of Health of the Russian Federation, Russian Clinical and Research Center of Gerontology, MoscowPirogov Russian National Research Medical University of the Ministry of Health of the Russian Federation, Russian Clinical and Research Center of Gerontology, MoscowPirogov Russian National Research Medical University of the Ministry of Health of the Russian Federation, Russian Clinical and Research Center of Gerontology, MoscowAbstract. The demographic aging of the population of the earth observed in recent years is associated, inter alia, with the advent of new effective and safe medicines. However, the availability of highly effective drugs on the market also has a reverse side — the appearance of adverse drug reactions (ADRs), in particular as a result of drug-drug interactions. The use of non-pharmacological methods of treatment and prevention of diseases seems particularly relevant for patients of the older age group, as it allows not only to reduce the drug burden, to reduce the risk of ADRs but also to improve the patient’s state in case of diseases that have no effective pharmacotherapy and pharmacological prophylaxis. The aim of the study was to systematize and analyze data on non-pharmacological treatment methods in order to increase the safety of pharmacotherapy and prevent polypragmasia in elderly patients by informing health care providers about non-drug methods of correcting significant geriatric problems. The approaches to the correction of some major geriatric problems (delirium, sarcopenia, pain syndrome), including cognitive training, physical activity, diet, frequent reorientation of patients, placement of patients in specially equipped rooms («delirium room») were presented. The use of non-pharmacological approaches can significantly improve the safety of drug therapy, reduce the risks of ADRs, improve the patient’s prognosis and quality of life, and also effectively prevent polypharmacy.https://www.risksafety.ru/jour/article/view/129pharmacotherapyprophylaxisoptimization of therapypolypharmacyelderly patientsdeliriumsarcopeniapain syndrome
spellingShingle A. P. Pereverzev
O. N. Tkacheva
Yu. V. Kotovskaya
Yu. S. Onuchina
E. N. Dudinskaya
A. V. Naumov
Non-pharmacological Approaches to Treatment of Patients over 60 Years as a Way to Improve Pharmacotherapy Safety and Prevent Polypharmacy
Безопасность и риск фармакотерапии
pharmacotherapy
prophylaxis
optimization of therapy
polypharmacy
elderly patients
delirium
sarcopenia
pain syndrome
title Non-pharmacological Approaches to Treatment of Patients over 60 Years as a Way to Improve Pharmacotherapy Safety and Prevent Polypharmacy
title_full Non-pharmacological Approaches to Treatment of Patients over 60 Years as a Way to Improve Pharmacotherapy Safety and Prevent Polypharmacy
title_fullStr Non-pharmacological Approaches to Treatment of Patients over 60 Years as a Way to Improve Pharmacotherapy Safety and Prevent Polypharmacy
title_full_unstemmed Non-pharmacological Approaches to Treatment of Patients over 60 Years as a Way to Improve Pharmacotherapy Safety and Prevent Polypharmacy
title_short Non-pharmacological Approaches to Treatment of Patients over 60 Years as a Way to Improve Pharmacotherapy Safety and Prevent Polypharmacy
title_sort non pharmacological approaches to treatment of patients over 60 years as a way to improve pharmacotherapy safety and prevent polypharmacy
topic pharmacotherapy
prophylaxis
optimization of therapy
polypharmacy
elderly patients
delirium
sarcopenia
pain syndrome
url https://www.risksafety.ru/jour/article/view/129
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