Quantitative Analysis of Matrine in Liquid Crystalline Nanoparticles by HPLC

A reversed-phase high-performance liquid chromatographic method has been developed to quantitatively determine matrine in liquid crystal nanoparticles. The chromatographic method is carried out using an isocratic system. The mobile phase was composed of methanol-PBS(pH6.8)-triethylamine (50 : 50 : 0...

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Main Authors: Xinsheng Peng, Baohong Li, Min Hu, Yahao Ling, Yuan Tian, Yanxing Zhou, Yanfang Zhou
Format: Article
Language:English
Published: Wiley 2014-01-01
Series:Journal of Analytical Methods in Chemistry
Online Access:http://dx.doi.org/10.1155/2014/368682
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author Xinsheng Peng
Baohong Li
Min Hu
Yahao Ling
Yuan Tian
Yanxing Zhou
Yanfang Zhou
author_facet Xinsheng Peng
Baohong Li
Min Hu
Yahao Ling
Yuan Tian
Yanxing Zhou
Yanfang Zhou
author_sort Xinsheng Peng
collection DOAJ
description A reversed-phase high-performance liquid chromatographic method has been developed to quantitatively determine matrine in liquid crystal nanoparticles. The chromatographic method is carried out using an isocratic system. The mobile phase was composed of methanol-PBS(pH6.8)-triethylamine (50 : 50 : 0.1%) with a flow rate of 1 mL/min with SPD-20A UV/vis detector and the detection wavelength was at 220 nm. The linearity of matrine is in the range of 1.6 to 200.0 μg/mL. The regression equation is y=10706x-2959 (R2=1.0). The average recovery is 101.7%; RSD=2.22%  (n=9). This method provides a simple and accurate strategy to determine matrine in liquid crystalline nanoparticle.
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id doaj-art-1883ec24cd2d47ea805287bdbe9191da
institution Kabale University
issn 2090-8865
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language English
publishDate 2014-01-01
publisher Wiley
record_format Article
series Journal of Analytical Methods in Chemistry
spelling doaj-art-1883ec24cd2d47ea805287bdbe9191da2025-08-20T03:54:12ZengWileyJournal of Analytical Methods in Chemistry2090-88652090-88732014-01-01201410.1155/2014/368682368682Quantitative Analysis of Matrine in Liquid Crystalline Nanoparticles by HPLCXinsheng Peng0Baohong Li1Min Hu2Yahao Ling3Yuan Tian4Yanxing Zhou5Yanfang Zhou6Guangdong Medical College, Xincheng Avenue, Guangdong 523808, ChinaGuangdong Medical College, Xincheng Avenue, Guangdong 523808, ChinaGuangdong Medical College, Xincheng Avenue, Guangdong 523808, ChinaGuangdong Medical College, Xincheng Avenue, Guangdong 523808, ChinaGuangdong Medical College, Xincheng Avenue, Guangdong 523808, ChinaGuangdong Medical College, Xincheng Avenue, Guangdong 523808, ChinaGuangdong Medical College, Xincheng Avenue, Guangdong 523808, ChinaA reversed-phase high-performance liquid chromatographic method has been developed to quantitatively determine matrine in liquid crystal nanoparticles. The chromatographic method is carried out using an isocratic system. The mobile phase was composed of methanol-PBS(pH6.8)-triethylamine (50 : 50 : 0.1%) with a flow rate of 1 mL/min with SPD-20A UV/vis detector and the detection wavelength was at 220 nm. The linearity of matrine is in the range of 1.6 to 200.0 μg/mL. The regression equation is y=10706x-2959 (R2=1.0). The average recovery is 101.7%; RSD=2.22%  (n=9). This method provides a simple and accurate strategy to determine matrine in liquid crystalline nanoparticle.http://dx.doi.org/10.1155/2014/368682
spellingShingle Xinsheng Peng
Baohong Li
Min Hu
Yahao Ling
Yuan Tian
Yanxing Zhou
Yanfang Zhou
Quantitative Analysis of Matrine in Liquid Crystalline Nanoparticles by HPLC
Journal of Analytical Methods in Chemistry
title Quantitative Analysis of Matrine in Liquid Crystalline Nanoparticles by HPLC
title_full Quantitative Analysis of Matrine in Liquid Crystalline Nanoparticles by HPLC
title_fullStr Quantitative Analysis of Matrine in Liquid Crystalline Nanoparticles by HPLC
title_full_unstemmed Quantitative Analysis of Matrine in Liquid Crystalline Nanoparticles by HPLC
title_short Quantitative Analysis of Matrine in Liquid Crystalline Nanoparticles by HPLC
title_sort quantitative analysis of matrine in liquid crystalline nanoparticles by hplc
url http://dx.doi.org/10.1155/2014/368682
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