Occupationally Relevant Zinc‐ and Copper‐Containing Metal Fumes Inhibit Human THP‐1 Macrophage TNF and IL‐6 Responses to Bacterial Stimuli

Occupationally Relevant Zinc‐ and Copper‐Containing Metal Fumes Inhibit Human THP‐1 Macrophage TNF and IL‐6 Responses to Bacterial Stimuli

Abstract Metal workers have an increased risk of severe lobar pneumonia due to exposure to metal fume particles, which lead to recent pneumococcal vaccination recommendations. To investigate the effects of metal fume‐derived zinc oxide (ZnO) and copper oxide (CuO) particles on airway immune response...

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Bibliographic Details
Main Authors:	Jan Steffens, Sabrina Michael, Katharina Kuth, Henner Hollert, Miriam Du Marchie Sarvaas, Andrijana Nesic, Thomas Kraus, Ralf Baumann
Format:	Article
Language:	English
Published:	Wiley 2025-05-01
Series:	Global Challenges
Subjects:	CuO/ZnO particles immunosuppressive effects on macrophages metal (nano)‐particle exposure welding and metal fumes workplace safety and new approach methodologies (NAM)
Online Access:	https://doi.org/10.1002/gch2.202400302
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