Results of neurotrophic keratopathy treatment by direct corneal neurotization

Relevance. Trigeminal nerve defeat can lead to the development of neurotrophic keratopathy. The only pathogenetically justified method of treating this pathology is corneal neurotization. Purpose. To develop rehabilitation tactic for the patients with neurotrophic keratopathy based on the analysis o...

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Main Authors: M.B. Gushchina, S.B. Butsan, V.Yu. Sergeeva, K.S. Salikhov, A.V. Tereshchenko, E.V. Erokhina, S.A. Mal’kov
Format: Article
Language:Russian
Published: Publishing house "Ophthalmology" 2023-11-01
Series:Офтальмохирургия
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Online Access:https://ophthalmosurgery.ru/index.php/ophthalmosurgery/article/view/549/810
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author M.B. Gushchina
S.B. Butsan
V.Yu. Sergeeva
K.S. Salikhov
A.V. Tereshchenko
E.V. Erokhina
S.A. Mal’kov
author_facet M.B. Gushchina
S.B. Butsan
V.Yu. Sergeeva
K.S. Salikhov
A.V. Tereshchenko
E.V. Erokhina
S.A. Mal’kov
author_sort M.B. Gushchina
collection DOAJ
description Relevance. Trigeminal nerve defeat can lead to the development of neurotrophic keratopathy. The only pathogenetically justified method of treating this pathology is corneal neurotization. Purpose. To develop rehabilitation tactic for the patients with neurotrophic keratopathy based on the analysis of the results of operations performed according to the author’s technique of direct corneal neurotization. Material and methods. 10 direct corneal neurotizations: with initial manifestations – in 2 cases and in the advanced stage of neurotrophic keratopathy – in 8 cases. Results and discussion. Postoperative period proceeded without complications. Corneal sensitivity was restored in 60%. In all cases, corneal transparency improved, the density of the eyesore and the depth of the invasion of opacities decreased, subbasal nerve fibers began to be visualized, positive dynamic in the state of tear production were observed. Perforation defects of the cornea was closed. In initial stage of the disease corneal opacity has almost completely regressed. Conclusion. Direct corneal neurotization provides restoration of its sensitivity, prevention of neurotrophic keratopathy, which provides medical and social rehabilitation.
format Article
id doaj-art-1870c4a8ea2442b89698d75d170d8147
institution Kabale University
issn 0235-4160
2312-4970
language Russian
publishDate 2023-11-01
publisher Publishing house "Ophthalmology"
record_format Article
series Офтальмохирургия
spelling doaj-art-1870c4a8ea2442b89698d75d170d81472025-08-20T03:44:24ZrusPublishing house "Ophthalmology"Офтальмохирургия0235-41602312-49702023-11-011363s374810.25276/0235-4160-2023-3S-37-48Results of neurotrophic keratopathy treatment by direct corneal neurotizationM.B. Gushchina0https://orcid.org/0000-0003-1134-8064S.B. Butsan1https://orcid.org/0000-0002-4013-8472V.Yu. Sergeeva2https://orcid.org/0000-0001-6568-2549K.S. Salikhov3https://orcid.org/0000-0003-1691-9516A.V. Tereshchenko4https://orcid.org/0000-0002-0840-2675E.V. Erokhina5https://orcid.org/0000-0001-7320-9209S.A. Mal’kov6https://orcid.org/0000-0003-0482-8254Central Research Institute of Dental and Maxillofacial Surgery, Moscow, Russian Federation; S. Fyodorov Eye Microsurgery Federal State Institution, Kaluga branch, Kaluga, Russian FederationCentral Research Institute of Dental and Maxillofacial Surgery, Moscow, Russian FederationCentral Research Institute of Dental and Maxillofacial Surgery, Moscow, Russian FederationCentral Research Institute of Dental and Maxillofacial Surgery, Moscow, Russian FederationS. Fyodorov Eye Microsurgery Federal State Institution, Kaluga branch, Kaluga, Russian FederationS. Fyodorov Eye Microsurgery Federal State Institution, Kaluga branch, Kaluga, Russian FederationRussian Medical Academy of Continuing Professional Education of the Ministry of Health, Moscow, Russian FederationRelevance. Trigeminal nerve defeat can lead to the development of neurotrophic keratopathy. The only pathogenetically justified method of treating this pathology is corneal neurotization. Purpose. To develop rehabilitation tactic for the patients with neurotrophic keratopathy based on the analysis of the results of operations performed according to the author’s technique of direct corneal neurotization. Material and methods. 10 direct corneal neurotizations: with initial manifestations – in 2 cases and in the advanced stage of neurotrophic keratopathy – in 8 cases. Results and discussion. Postoperative period proceeded without complications. Corneal sensitivity was restored in 60%. In all cases, corneal transparency improved, the density of the eyesore and the depth of the invasion of opacities decreased, subbasal nerve fibers began to be visualized, positive dynamic in the state of tear production were observed. Perforation defects of the cornea was closed. In initial stage of the disease corneal opacity has almost completely regressed. Conclusion. Direct corneal neurotization provides restoration of its sensitivity, prevention of neurotrophic keratopathy, which provides medical and social rehabilitation.https://ophthalmosurgery.ru/index.php/ophthalmosurgery/article/view/549/810facial nerveparalytic lagophthalmosabductive nerveconvergent paralytic strabismustrigeminal nervecorneal innervationcorneal opacitycorneal sensitivityesthesiometrysupraorbital nerve
spellingShingle M.B. Gushchina
S.B. Butsan
V.Yu. Sergeeva
K.S. Salikhov
A.V. Tereshchenko
E.V. Erokhina
S.A. Mal’kov
Results of neurotrophic keratopathy treatment by direct corneal neurotization
Офтальмохирургия
facial nerve
paralytic lagophthalmos
abductive nerve
convergent paralytic strabismus
trigeminal nerve
corneal innervation
corneal opacity
corneal sensitivity
esthesiometry
supraorbital nerve
title Results of neurotrophic keratopathy treatment by direct corneal neurotization
title_full Results of neurotrophic keratopathy treatment by direct corneal neurotization
title_fullStr Results of neurotrophic keratopathy treatment by direct corneal neurotization
title_full_unstemmed Results of neurotrophic keratopathy treatment by direct corneal neurotization
title_short Results of neurotrophic keratopathy treatment by direct corneal neurotization
title_sort results of neurotrophic keratopathy treatment by direct corneal neurotization
topic facial nerve
paralytic lagophthalmos
abductive nerve
convergent paralytic strabismus
trigeminal nerve
corneal innervation
corneal opacity
corneal sensitivity
esthesiometry
supraorbital nerve
url https://ophthalmosurgery.ru/index.php/ophthalmosurgery/article/view/549/810
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