Neuroplasticity and functional reorganization of language in patients with arteriovenous malformations: insights from neuroimaging and clinical interventions
Patients with arteriovenous malformations (AVMs) located in the functional area of speech often exhibit language dysfunction, and neuroplasticity allows the brain of some patients to regain speech through functional reorganization. Exploring the mechanism of AVMs-induced reorganization of language f...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2025-01-01
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| Series: | Frontiers in Human Neuroscience |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fnhum.2025.1503864/full |
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| author | Jialong Yuan Hongchuan Niu Chengxu Lei Ruichen Xu Yutong Liu Kexin Yuan Linru Zou Shihao He Shihao He Yuanli Zhao Yuanli Zhao |
| author_facet | Jialong Yuan Hongchuan Niu Chengxu Lei Ruichen Xu Yutong Liu Kexin Yuan Linru Zou Shihao He Shihao He Yuanli Zhao Yuanli Zhao |
| author_sort | Jialong Yuan |
| collection | DOAJ |
| description | Patients with arteriovenous malformations (AVMs) located in the functional area of speech often exhibit language dysfunction, and neuroplasticity allows the brain of some patients to regain speech through functional reorganization. Exploring the mechanism of AVMs-induced reorganization of language function is important for understanding neuroplasticity and improving clinical intervention strategies. This review systematically searched and analyzed the research literature in related fields in recent years, covering data from neuroimaging, functional magnetic resonance imaging (fMRI), and clinical case studies. By integrating these evidences, the phenomenon of functional reorganization within non-verbal functional areas and its influencing factors in patients with AVMs were assessed. It concluded that functional reorganization of language due to AVMs is a manifestation of a high degree of neurological plasticity and that understanding this process has important implications for neurosurgical planning and postoperative rehabilitation of patients. Future research should continue to explore the mechanisms of functional reorganization in the brain and work to develop new diagnostic tools and therapeutic approaches to improve the rate of recovery of language function in patients with AVMs. |
| format | Article |
| id | doaj-art-186a1dbc7fe848fa9cf250013df3841e |
| institution | Kabale University |
| issn | 1662-5161 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Human Neuroscience |
| spelling | doaj-art-186a1dbc7fe848fa9cf250013df3841e2025-01-31T06:40:00ZengFrontiers Media S.A.Frontiers in Human Neuroscience1662-51612025-01-011910.3389/fnhum.2025.15038641503864Neuroplasticity and functional reorganization of language in patients with arteriovenous malformations: insights from neuroimaging and clinical interventionsJialong Yuan0Hongchuan Niu1Chengxu Lei2Ruichen Xu3Yutong Liu4Kexin Yuan5Linru Zou6Shihao He7Shihao He8Yuanli Zhao9Yuanli Zhao10Department of Neurosurgery, Peking Union Medical College Hospital, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing, ChinaDepartment of Neurosurgery, Peking University International Hospital, Beijing, ChinaDepartment of Neurosurgery, Peking Union Medical College Hospital, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing, ChinaDepartment of Neurosurgery, Peking Union Medical College Hospital, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing, ChinaDepartment of Neurosurgery, Peking Union Medical College Hospital, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing, ChinaDepartment of Neurosurgery, Peking Union Medical College Hospital, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing, ChinaDepartment of Neurosurgery, Peking Union Medical College Hospital, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing, ChinaDepartment of Neurosurgery, Peking Union Medical College Hospital, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing, ChinaDepartment of Neurosurgery, Peking University International Hospital, Beijing, ChinaDepartment of Neurosurgery, Peking Union Medical College Hospital, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing, ChinaDepartment of Neurosurgery, Peking University International Hospital, Beijing, ChinaPatients with arteriovenous malformations (AVMs) located in the functional area of speech often exhibit language dysfunction, and neuroplasticity allows the brain of some patients to regain speech through functional reorganization. Exploring the mechanism of AVMs-induced reorganization of language function is important for understanding neuroplasticity and improving clinical intervention strategies. This review systematically searched and analyzed the research literature in related fields in recent years, covering data from neuroimaging, functional magnetic resonance imaging (fMRI), and clinical case studies. By integrating these evidences, the phenomenon of functional reorganization within non-verbal functional areas and its influencing factors in patients with AVMs were assessed. It concluded that functional reorganization of language due to AVMs is a manifestation of a high degree of neurological plasticity and that understanding this process has important implications for neurosurgical planning and postoperative rehabilitation of patients. Future research should continue to explore the mechanisms of functional reorganization in the brain and work to develop new diagnostic tools and therapeutic approaches to improve the rate of recovery of language function in patients with AVMs.https://www.frontiersin.org/articles/10.3389/fnhum.2025.1503864/fullarteriovenous malformationfunctional speech areareorganization of speech functionfunctional magnetic resonance imagingtargeted preoperative assessments |
| spellingShingle | Jialong Yuan Hongchuan Niu Chengxu Lei Ruichen Xu Yutong Liu Kexin Yuan Linru Zou Shihao He Shihao He Yuanli Zhao Yuanli Zhao Neuroplasticity and functional reorganization of language in patients with arteriovenous malformations: insights from neuroimaging and clinical interventions Frontiers in Human Neuroscience arteriovenous malformation functional speech area reorganization of speech function functional magnetic resonance imaging targeted preoperative assessments |
| title | Neuroplasticity and functional reorganization of language in patients with arteriovenous malformations: insights from neuroimaging and clinical interventions |
| title_full | Neuroplasticity and functional reorganization of language in patients with arteriovenous malformations: insights from neuroimaging and clinical interventions |
| title_fullStr | Neuroplasticity and functional reorganization of language in patients with arteriovenous malformations: insights from neuroimaging and clinical interventions |
| title_full_unstemmed | Neuroplasticity and functional reorganization of language in patients with arteriovenous malformations: insights from neuroimaging and clinical interventions |
| title_short | Neuroplasticity and functional reorganization of language in patients with arteriovenous malformations: insights from neuroimaging and clinical interventions |
| title_sort | neuroplasticity and functional reorganization of language in patients with arteriovenous malformations insights from neuroimaging and clinical interventions |
| topic | arteriovenous malformation functional speech area reorganization of speech function functional magnetic resonance imaging targeted preoperative assessments |
| url | https://www.frontiersin.org/articles/10.3389/fnhum.2025.1503864/full |
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