POSITIVE RESULTS OF TRANSPLANTATION OF MULTI-COMPONENT COMPOSITE MATERIAL CONTAINING ALLOGENEIC MESENCHYMAL STEM CELLS AFTER CYSTECTOMY IN A RABBIT
Of late much attention has been paid to tissue engineering by urologists. After successful testing on animals, artificial urinary bladders with self-specific cells were transplanted to humans. Our research is aimed at investigating the opportunity of using cellular technologies if no healthy self-...
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| Format: | Article |
| Language: | Russian |
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New Terra Publishing House
2017-06-01
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| Series: | Туберкулез и болезни лёгких |
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| Online Access: | https://www.tibl-journal.com/jour/article/view/1013 |
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| author | N. V. Orlovа T. I. Vinogrаdovа N. M. Yudintsevа Yu. A. Nаsсhekinа M. G. Sheykhov P. K. Yablonsky |
| author_facet | N. V. Orlovа T. I. Vinogrаdovа N. M. Yudintsevа Yu. A. Nаsсhekinа M. G. Sheykhov P. K. Yablonsky |
| author_sort | N. V. Orlovа |
| collection | DOAJ |
| description | Of late much attention has been paid to tissue engineering by urologists. After successful testing on animals, artificial urinary bladders with self-specific cells were transplanted to humans. Our research is aimed at investigating the opportunity of using cellular technologies if no healthy self-specific material is available.The goal of this experiment is to investigate the opportunity of using a multi-component composite material containing allogeneic cells to replace the defect of urinary wall under experimental conditions.The standard technique was used for isolation and culturing of mesenchymal stromal stem cells from the rabbit's bone marrow. Multi-component composite material based on the polylactide matrix was inoculated by allogeneic cells and transplanted in vivo to the model of partial cystectomy. In 2.5 months the presence of labeled cells in the implantation site was confirmed by objective methods. |
| format | Article |
| id | doaj-art-18693dfe4d4d483886d980a3dd7c64fd |
| institution | OA Journals |
| issn | 2075-1230 2542-1506 |
| language | Russian |
| publishDate | 2017-06-01 |
| publisher | New Terra Publishing House |
| record_format | Article |
| series | Туберкулез и болезни лёгких |
| spelling | doaj-art-18693dfe4d4d483886d980a3dd7c64fd2025-08-20T01:47:52ZrusNew Terra Publishing HouseТуберкулез и болезни лёгких2075-12302542-15062017-06-01956455010.21292/2075-1230-2017-95-6-45-501013POSITIVE RESULTS OF TRANSPLANTATION OF MULTI-COMPONENT COMPOSITE MATERIAL CONTAINING ALLOGENEIC MESENCHYMAL STEM CELLS AFTER CYSTECTOMY IN A RABBITN. V. Orlovа0T. I. Vinogrаdovа1N. M. Yudintsevа2Yu. A. Nаsсhekinа3M. G. Sheykhov4P. K. Yablonsky5St. Petersburg Research Institute of PhthisiopulmonologySt. Petersburg Research Institute of PhthisiopulmonologyInstitute of Cytology of the Russian Academy of ScienceInstitute of Cytology of the Russian Academy of ScienceSt. Petersburg Research Institute of PhthisiopulmonologySt. Petersburg Research Institute of Phthisiopulmonology; St. Petersburg UniversityOf late much attention has been paid to tissue engineering by urologists. After successful testing on animals, artificial urinary bladders with self-specific cells were transplanted to humans. Our research is aimed at investigating the opportunity of using cellular technologies if no healthy self-specific material is available.The goal of this experiment is to investigate the opportunity of using a multi-component composite material containing allogeneic cells to replace the defect of urinary wall under experimental conditions.The standard technique was used for isolation and culturing of mesenchymal stromal stem cells from the rabbit's bone marrow. Multi-component composite material based on the polylactide matrix was inoculated by allogeneic cells and transplanted in vivo to the model of partial cystectomy. In 2.5 months the presence of labeled cells in the implantation site was confirmed by objective methods.https://www.tibl-journal.com/jour/article/view/1013allogeneic transplantationmesenchymal stromal cells of bone marrowurinary bladdertissue engineering |
| spellingShingle | N. V. Orlovа T. I. Vinogrаdovа N. M. Yudintsevа Yu. A. Nаsсhekinа M. G. Sheykhov P. K. Yablonsky POSITIVE RESULTS OF TRANSPLANTATION OF MULTI-COMPONENT COMPOSITE MATERIAL CONTAINING ALLOGENEIC MESENCHYMAL STEM CELLS AFTER CYSTECTOMY IN A RABBIT Туберкулез и болезни лёгких allogeneic transplantation mesenchymal stromal cells of bone marrow urinary bladder tissue engineering |
| title | POSITIVE RESULTS OF TRANSPLANTATION OF MULTI-COMPONENT COMPOSITE MATERIAL CONTAINING ALLOGENEIC MESENCHYMAL STEM CELLS AFTER CYSTECTOMY IN A RABBIT |
| title_full | POSITIVE RESULTS OF TRANSPLANTATION OF MULTI-COMPONENT COMPOSITE MATERIAL CONTAINING ALLOGENEIC MESENCHYMAL STEM CELLS AFTER CYSTECTOMY IN A RABBIT |
| title_fullStr | POSITIVE RESULTS OF TRANSPLANTATION OF MULTI-COMPONENT COMPOSITE MATERIAL CONTAINING ALLOGENEIC MESENCHYMAL STEM CELLS AFTER CYSTECTOMY IN A RABBIT |
| title_full_unstemmed | POSITIVE RESULTS OF TRANSPLANTATION OF MULTI-COMPONENT COMPOSITE MATERIAL CONTAINING ALLOGENEIC MESENCHYMAL STEM CELLS AFTER CYSTECTOMY IN A RABBIT |
| title_short | POSITIVE RESULTS OF TRANSPLANTATION OF MULTI-COMPONENT COMPOSITE MATERIAL CONTAINING ALLOGENEIC MESENCHYMAL STEM CELLS AFTER CYSTECTOMY IN A RABBIT |
| title_sort | positive results of transplantation of multi component composite material containing allogeneic mesenchymal stem cells after cystectomy in a rabbit |
| topic | allogeneic transplantation mesenchymal stromal cells of bone marrow urinary bladder tissue engineering |
| url | https://www.tibl-journal.com/jour/article/view/1013 |
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