Innovative technologies to address neglected tropical diseases in African settings with persistent sociopolitical instability

Abstract The health, economic, and social burden of neglected tropical diseases (NTDs) in Africa remains substantial, with elimination efforts hindered by persistent sociopolitical instability, including ongoing conflicts among political and ethnic groups that lead to internal displacement and migra...

Full description

Saved in:
Bibliographic Details
Main Authors: Tsegahun Manyazewal, Gail Davey, Charlotte Hanlon, Melanie J. Newport, Michael Hopkins, Jenni Wilburn, Sahar Bakhiet, Leon Mutesa, Agumasie Semahegn, Esubalew Assefa, Abebaw Fekadu
Format: Article
Language:English
Published: Nature Portfolio 2024-11-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-024-54496-4
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1850064492880199680
author Tsegahun Manyazewal
Gail Davey
Charlotte Hanlon
Melanie J. Newport
Michael Hopkins
Jenni Wilburn
Sahar Bakhiet
Leon Mutesa
Agumasie Semahegn
Esubalew Assefa
Abebaw Fekadu
author_facet Tsegahun Manyazewal
Gail Davey
Charlotte Hanlon
Melanie J. Newport
Michael Hopkins
Jenni Wilburn
Sahar Bakhiet
Leon Mutesa
Agumasie Semahegn
Esubalew Assefa
Abebaw Fekadu
author_sort Tsegahun Manyazewal
collection DOAJ
description Abstract The health, economic, and social burden of neglected tropical diseases (NTDs) in Africa remains substantial, with elimination efforts hindered by persistent sociopolitical instability, including ongoing conflicts among political and ethnic groups that lead to internal displacement and migration. Here, we explore how innovative technologies can support Africa in addressing NTDs amidst such instability, through analysis of WHO and UNHCR data and a systematic literature review. Countries in Africa facing sociopolitical instability also bear a high burden of NTDs, with the continent ranking second globally in NTD burden (33%, 578 million people) and first in internal displacement (50%, 31.6 million people) in 2023. Studies have investigated technologies for their potential in NTD prevention, surveillance, diagnosis, treatment and management. Integrating the evidence, we discuss nine promising technologies—artificial intelligence, drones, mobile clinics, nanotechnology, telemedicine, augmented reality, advanced point-of-care diagnostics, mobile health Apps, and wearable sensors—that could enhance Africa’s response to NTDs in the face of persistent sociopolitical instability. As stability returns, these technologies will evolve to support more comprehensive and sustainable health development. The global health community should facilitate deployment of health technologies to those in greatest need to help achieve the NTD 2030 Roadmap and other global health targets.
format Article
id doaj-art-1867ffdd62c54f099eb67916ebc0c503
institution DOAJ
issn 2041-1723
language English
publishDate 2024-11-01
publisher Nature Portfolio
record_format Article
series Nature Communications
spelling doaj-art-1867ffdd62c54f099eb67916ebc0c5032025-08-20T02:49:17ZengNature PortfolioNature Communications2041-17232024-11-0115111710.1038/s41467-024-54496-4Innovative technologies to address neglected tropical diseases in African settings with persistent sociopolitical instabilityTsegahun Manyazewal0Gail Davey1Charlotte Hanlon2Melanie J. Newport3Michael Hopkins4Jenni Wilburn5Sahar Bakhiet6Leon Mutesa7Agumasie Semahegn8Esubalew Assefa9Abebaw Fekadu10Center for Innovative Drug Development and Therapeutic Trials for Africa (CDT-Africa), College of Health Sciences, Addis Ababa UniversityCentre for Global Health Research, Brighton and Sussex Medical SchoolCenter for Innovative Drug Development and Therapeutic Trials for Africa (CDT-Africa), College of Health Sciences, Addis Ababa UniversityCentre for Global Health Research, Brighton and Sussex Medical SchoolScience Policy Research Unit, University of SussexCentre for Global Health Research, Brighton and Sussex Medical SchoolInstitute of Endemic Diseases, University of KhartoumCenter for Human Genetics, College of Medicine and Health Sciences, University of RwandaCenter for Innovative Drug Development and Therapeutic Trials for Africa (CDT-Africa), College of Health Sciences, Addis Ababa UniversityCenter for Innovative Drug Development and Therapeutic Trials for Africa (CDT-Africa), College of Health Sciences, Addis Ababa UniversityCenter for Innovative Drug Development and Therapeutic Trials for Africa (CDT-Africa), College of Health Sciences, Addis Ababa UniversityAbstract The health, economic, and social burden of neglected tropical diseases (NTDs) in Africa remains substantial, with elimination efforts hindered by persistent sociopolitical instability, including ongoing conflicts among political and ethnic groups that lead to internal displacement and migration. Here, we explore how innovative technologies can support Africa in addressing NTDs amidst such instability, through analysis of WHO and UNHCR data and a systematic literature review. Countries in Africa facing sociopolitical instability also bear a high burden of NTDs, with the continent ranking second globally in NTD burden (33%, 578 million people) and first in internal displacement (50%, 31.6 million people) in 2023. Studies have investigated technologies for their potential in NTD prevention, surveillance, diagnosis, treatment and management. Integrating the evidence, we discuss nine promising technologies—artificial intelligence, drones, mobile clinics, nanotechnology, telemedicine, augmented reality, advanced point-of-care diagnostics, mobile health Apps, and wearable sensors—that could enhance Africa’s response to NTDs in the face of persistent sociopolitical instability. As stability returns, these technologies will evolve to support more comprehensive and sustainable health development. The global health community should facilitate deployment of health technologies to those in greatest need to help achieve the NTD 2030 Roadmap and other global health targets.https://doi.org/10.1038/s41467-024-54496-4
spellingShingle Tsegahun Manyazewal
Gail Davey
Charlotte Hanlon
Melanie J. Newport
Michael Hopkins
Jenni Wilburn
Sahar Bakhiet
Leon Mutesa
Agumasie Semahegn
Esubalew Assefa
Abebaw Fekadu
Innovative technologies to address neglected tropical diseases in African settings with persistent sociopolitical instability
Nature Communications
title Innovative technologies to address neglected tropical diseases in African settings with persistent sociopolitical instability
title_full Innovative technologies to address neglected tropical diseases in African settings with persistent sociopolitical instability
title_fullStr Innovative technologies to address neglected tropical diseases in African settings with persistent sociopolitical instability
title_full_unstemmed Innovative technologies to address neglected tropical diseases in African settings with persistent sociopolitical instability
title_short Innovative technologies to address neglected tropical diseases in African settings with persistent sociopolitical instability
title_sort innovative technologies to address neglected tropical diseases in african settings with persistent sociopolitical instability
url https://doi.org/10.1038/s41467-024-54496-4
work_keys_str_mv AT tsegahunmanyazewal innovativetechnologiestoaddressneglectedtropicaldiseasesinafricansettingswithpersistentsociopoliticalinstability
AT gaildavey innovativetechnologiestoaddressneglectedtropicaldiseasesinafricansettingswithpersistentsociopoliticalinstability
AT charlottehanlon innovativetechnologiestoaddressneglectedtropicaldiseasesinafricansettingswithpersistentsociopoliticalinstability
AT melaniejnewport innovativetechnologiestoaddressneglectedtropicaldiseasesinafricansettingswithpersistentsociopoliticalinstability
AT michaelhopkins innovativetechnologiestoaddressneglectedtropicaldiseasesinafricansettingswithpersistentsociopoliticalinstability
AT jenniwilburn innovativetechnologiestoaddressneglectedtropicaldiseasesinafricansettingswithpersistentsociopoliticalinstability
AT saharbakhiet innovativetechnologiestoaddressneglectedtropicaldiseasesinafricansettingswithpersistentsociopoliticalinstability
AT leonmutesa innovativetechnologiestoaddressneglectedtropicaldiseasesinafricansettingswithpersistentsociopoliticalinstability
AT agumasiesemahegn innovativetechnologiestoaddressneglectedtropicaldiseasesinafricansettingswithpersistentsociopoliticalinstability
AT esubalewassefa innovativetechnologiestoaddressneglectedtropicaldiseasesinafricansettingswithpersistentsociopoliticalinstability
AT abebawfekadu innovativetechnologiestoaddressneglectedtropicaldiseasesinafricansettingswithpersistentsociopoliticalinstability