Diverse effects of coronavirus-defective viral genomes on the synthesis of IFNβ and ISG15 mRNAs and coronavirus replication

Diverse effects of coronavirus-defective viral genomes on the synthesis of IFNβ and ISG15 mRNAs and coronavirus replication

Abstract Background The mechanism by which coronavirus-defective viral genomes (DVGs) affect coronavirus and host cells during infection remains unclear. A variety of DVGs with different RNA structures can be synthesized from coronavirus-infected cells, and these DVGs can also encode proteins. Conse...

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Bibliographic Details
Main Authors: Hsuan-Wei Hsu, Li-Kang Chang, Chun-Chun Yang, Ching-Hung Lin, Yu Teng, Pei-Chi Hsu, Cheng-Yao Yang, Hung-Yi Wu
Format: Article
Language:English
Published: BMC 2025-02-01
Series:Virology Journal
Online Access:https://doi.org/10.1186/s12985-025-02654-5
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