SALSA: a novel flow cytometry assay to detect ascorbate at the single-cell level

SALSA: a novel flow cytometry assay to detect ascorbate at the single-cell level

Ascorbate (AA) is an essential antioxidant and enzymatic cofactor with emerging roles in epigenetic regulation, redox biology, and immune function. However, single-cell quantification of intracellular AA has remained technically challenging. Here, we present SALSA (Single-cell Ascorbate Level Sensin...

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Bibliographic Details
Main Authors: Bella Lee, Wendy Wan-Ting Chou, Heng-Yi Chen, Dena Mossad, Michael Hsu, Bridget Bowman, Kartick Patra, Huan Zhang, Fang-Yun Lay, Frederick A. Villamena, Gang Xin, Richard S Bruno, Mark Levine, Jiangjiang Zhu, Fernanda Novais, Chan-Wang Jerry Lio
Format: Article
Language:English
Published: Elsevier 2025-10-01
Series:Redox Biology
Subjects:
Ascorbate
Vitamin C
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231725003362
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