Ionotropic Gelation and Chemical Crosslinking as Tools to Obtain Gellan Gum-Based Beads with Mesalazine

Ionotropic Gelation and Chemical Crosslinking as Tools to Obtain Gellan Gum-Based Beads with Mesalazine

<b>Introduction:</b> Many orally administered drugs are either unstable in the acidic environment of the stomach or cause moderate to severe side effects in the upper gastrointestinal tract (GIT). These limitations can reduce therapeutic efficacy, discourage patient compliance, worsen th...

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Main Authors: Piotr Gadziński, Agnieszka Skotnicka, Natalia Lisiak, Ewa Totoń, Błażej Rubiś, Ewa Florek, Dariusz T. Mlynarczyk, Mirosław Szybowicz, Ewelina Nowak, Tomasz Osmałek
Format: Article
Language:English
Published: MDPI AG 2025-04-01
Series:Pharmaceutics
Subjects:
gellan gum
ionotropic gelation
modified release
bioavailability
drug delivery
Online Access:https://www.mdpi.com/1999-4923/17/5/569
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