Deep mutational scanning and CRISPR-engineered viruses: tools for evolutionary and functional genomics studies

ABSTRACT Recent advancements in synthetic biology and sequencing technologies have revolutionized the ability to manipulate viral genomes with unparalleled precision. This review focuses on two powerful methodologies: deep mutational scanning and CRISPR-based genome editing, that enable comprehensiv...

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Bibliographic Details
Main Authors: Mercedes Paz, Gonzalo Moratorio
Format: Article
Language:English
Published: American Society for Microbiology 2025-05-01
Series:mSphere
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Online Access:https://journals.asm.org/doi/10.1128/msphere.00508-24
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