Etiological and epidemiological features of concomitant acute intestinal infections in children
Objective: to study the frequency, etiological, age, epidemiological features of combined acute intestinal infections in children.Materials and methods. In n the Department of intestinal infections of Pediatric Research and Clinical Center for Infectious Diseases within a year have observed 167 chi...
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| Language: | Russian |
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Journal Infectology
2020-06-01
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| Series: | Журнал инфектологии |
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| Online Access: | https://journal.niidi.ru/jofin/article/view/1055 |
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| author | N. V. Gonchar I. V. Razd`yakonova N. V. Skripchenko S. G. Grigor’ev |
| author_facet | N. V. Gonchar I. V. Razd`yakonova N. V. Skripchenko S. G. Grigor’ev |
| author_sort | N. V. Gonchar |
| collection | DOAJ |
| description | Objective: to study the frequency, etiological, age, epidemiological features of combined acute intestinal infections in children.Materials and methods. In n the Department of intestinal infections of Pediatric Research and Clinical Center for Infectious Diseases within a year have observed 167 children with combined acute intestinal infections regardless of the severity of the disease. The etiology of the acute intestinal infections was verified by bacteriological, serological methods, PCR reagents “AmpliSens® AII screen-FL. Criteria for inclusion of patients in the study: no signs of nosocomial OKA. Statistical analysis of the results was performed using Excel 2007. Student’s criterion was used to estimate the difference of the studied data. Differences were considered significant at p<0.05. Results. Combined acute intestinal infections were diagnosed in 5,6% of 2968 patients, among whom children under 1 year were 21,6%, from 1 to 3 years – 48,4%, from 4 to 7 years – 18%, from 8 to 14 years – 9%, from 14 to 18 years – 3%. The combination of bacterial pathogens was noted in 12% of patients; viral – in 37,1%; viral and bacterial – in 50,9%. Viral-bacterial AII had rises in the frequency of diagnosis in spring, summer, autumn; viral-viral acute intestinal infections – in spring and autumn, bacterial-bacterial acute intestinal infections – in autumn. Infants in the structure of patients with viral-viral acute intestinal infections were 23,3%, viral-bacterial acute intestinal infections – 29,6%, bacterial-bacterial acute intestinal infections – 5%; young age – 45%; 47,%; 40%; preschool age– 25%; 23,3%; 15,5%; school age – 30%; 8.3%; 7% respectively. Among of associates the bacterial-bacterial acute intestinal infections, diarrheal Escherichia (60%), Salmonella (50%) and Campylobacters (40%) dominated. Among of associates of the viral-viral acute intestinal infections noroviruses (74,2%) and rotaviruses (at 69,4%) dominated. Among of viral associates of viral-bacterial acute intestinal infections more prevalent were rotaviruses (52,9%) and noroviruses (27,1%); among bacterial associates were diarrheal Escherichia (at 51,8%).The results of the study allowed establish etiological, seasonal, age patterns of formation of the epidemiological process of intestinal infections of combined etiology in children. |
| format | Article |
| id | doaj-art-1826c2fe27e048559ce3a7461b732d92 |
| institution | DOAJ |
| issn | 2072-6732 |
| language | Russian |
| publishDate | 2020-06-01 |
| publisher | Journal Infectology |
| record_format | Article |
| series | Журнал инфектологии |
| spelling | doaj-art-1826c2fe27e048559ce3a7461b732d922025-08-20T02:55:13ZrusJournal InfectologyЖурнал инфектологии2072-67322020-06-0112211311810.22625/2072-6732-2020-12-2-113-118813Etiological and epidemiological features of concomitant acute intestinal infections in childrenN. V. Gonchar0I. V. Razd`yakonova1N. V. Skripchenko2S. G. Grigor’ev3Pediatric Research and Clinical Center for Infectious Diseases; North-Western State Medical University named after I.I. MechnikovPediatric Research and Clinical Center for Infectious DiseasesPediatric Research and Clinical Center for Infectious Diseases; Saint-Petersburg State Pediatric Medical UniversityPediatric Research and Clinical Center for Infectious Diseases; Military Medical Academy named after S.M. KirovObjective: to study the frequency, etiological, age, epidemiological features of combined acute intestinal infections in children.Materials and methods. In n the Department of intestinal infections of Pediatric Research and Clinical Center for Infectious Diseases within a year have observed 167 children with combined acute intestinal infections regardless of the severity of the disease. The etiology of the acute intestinal infections was verified by bacteriological, serological methods, PCR reagents “AmpliSens® AII screen-FL. Criteria for inclusion of patients in the study: no signs of nosocomial OKA. Statistical analysis of the results was performed using Excel 2007. Student’s criterion was used to estimate the difference of the studied data. Differences were considered significant at p<0.05. Results. Combined acute intestinal infections were diagnosed in 5,6% of 2968 patients, among whom children under 1 year were 21,6%, from 1 to 3 years – 48,4%, from 4 to 7 years – 18%, from 8 to 14 years – 9%, from 14 to 18 years – 3%. The combination of bacterial pathogens was noted in 12% of patients; viral – in 37,1%; viral and bacterial – in 50,9%. Viral-bacterial AII had rises in the frequency of diagnosis in spring, summer, autumn; viral-viral acute intestinal infections – in spring and autumn, bacterial-bacterial acute intestinal infections – in autumn. Infants in the structure of patients with viral-viral acute intestinal infections were 23,3%, viral-bacterial acute intestinal infections – 29,6%, bacterial-bacterial acute intestinal infections – 5%; young age – 45%; 47,%; 40%; preschool age– 25%; 23,3%; 15,5%; school age – 30%; 8.3%; 7% respectively. Among of associates the bacterial-bacterial acute intestinal infections, diarrheal Escherichia (60%), Salmonella (50%) and Campylobacters (40%) dominated. Among of associates of the viral-viral acute intestinal infections noroviruses (74,2%) and rotaviruses (at 69,4%) dominated. Among of viral associates of viral-bacterial acute intestinal infections more prevalent were rotaviruses (52,9%) and noroviruses (27,1%); among bacterial associates were diarrheal Escherichia (at 51,8%).The results of the study allowed establish etiological, seasonal, age patterns of formation of the epidemiological process of intestinal infections of combined etiology in children.https://journal.niidi.ru/jofin/article/view/1055combined intestinal infectionschildrenetiologyepidemiology |
| spellingShingle | N. V. Gonchar I. V. Razd`yakonova N. V. Skripchenko S. G. Grigor’ev Etiological and epidemiological features of concomitant acute intestinal infections in children Журнал инфектологии combined intestinal infections children etiology epidemiology |
| title | Etiological and epidemiological features of concomitant acute intestinal infections in children |
| title_full | Etiological and epidemiological features of concomitant acute intestinal infections in children |
| title_fullStr | Etiological and epidemiological features of concomitant acute intestinal infections in children |
| title_full_unstemmed | Etiological and epidemiological features of concomitant acute intestinal infections in children |
| title_short | Etiological and epidemiological features of concomitant acute intestinal infections in children |
| title_sort | etiological and epidemiological features of concomitant acute intestinal infections in children |
| topic | combined intestinal infections children etiology epidemiology |
| url | https://journal.niidi.ru/jofin/article/view/1055 |
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