Multiple patterns of persistent inward currents with multiple types of repetitive firings in medullary serotonergic neurons of mice: An experimental and modeling study.

Multiple patterns of persistent inward currents with multiple types of repetitive firings in medullary serotonergic neurons of mice: An experimental and modeling study.

Persistent inward currents (PICs) play a crucial role in regulating neuronal excitability. These currents are composed of calcium (CaL) and sodium (NaP) components in vertebrate spinal neurons. Recent studies have reported that PICs are expressed in serotonergic neurons (5-HT) in medulla of mice. Mu...

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Bibliographic Details
Main Authors: Yi Cheng, Xingyu Wang, Qiang Zhang, Renkai Ge, Mei Zhou, Yue Dai
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2025-04-01
Series:PLoS Computational Biology
Online Access:https://doi.org/10.1371/journal.pcbi.1012918
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