The relationship between neurocysticercosis and epilepsy: an endless debate

Neurocysticercosis (NC), or cerebral infection with Taenia solium, is an important public health problem worldwide. Among the neurological sequelae of NC, seizures have been described as the most common symptom. Acute symptomatic seizures often result from degeneration of a viable cyst; however, not...

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Main Authors: Arturo Carpio, Matthew L. Romo
Format: Article
Language:English
Published: Thieme Revinter Publicações 2014-05-01
Series:Arquivos de Neuro-Psiquiatria
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Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2014000500383&lng=en&tlng=en
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author Arturo Carpio
Matthew L. Romo
author_facet Arturo Carpio
Matthew L. Romo
author_sort Arturo Carpio
collection DOAJ
description Neurocysticercosis (NC), or cerebral infection with Taenia solium, is an important public health problem worldwide. Among the neurological sequelae of NC, seizures have been described as the most common symptom. Acute symptomatic seizures often result from degeneration of a viable cyst; however, not all of these patients with acute or provoked seizures will develop epilepsy (i.e., recurrent unprovoked seizures). Because of the high prevalence of epilepsy and NC, a causal, as well as incidental relationship between the two may exist. The epileptogenicity of calcified cysts as well as the potential association between NC and hippocampal sclerosis necessitates future research. Antihelminthic treatment of NC results in disappearance of viable cysts in about one-third of patients with parenchymal disease, but a reduction in seizure recurrence has not been demonstrated in randomized controlled trials. Prevention is critical to reduce the burden of seizure and epilepsy related to NC.
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spelling doaj-art-1801ffd9c5cc4b16bf34a54277759f4a2025-08-20T03:54:20ZengThieme Revinter PublicaçõesArquivos de Neuro-Psiquiatria1678-42272014-05-0172538339010.1590/0004-282X20140024S0004-282X2014000500383The relationship between neurocysticercosis and epilepsy: an endless debateArturo CarpioMatthew L. RomoNeurocysticercosis (NC), or cerebral infection with Taenia solium, is an important public health problem worldwide. Among the neurological sequelae of NC, seizures have been described as the most common symptom. Acute symptomatic seizures often result from degeneration of a viable cyst; however, not all of these patients with acute or provoked seizures will develop epilepsy (i.e., recurrent unprovoked seizures). Because of the high prevalence of epilepsy and NC, a causal, as well as incidental relationship between the two may exist. The epileptogenicity of calcified cysts as well as the potential association between NC and hippocampal sclerosis necessitates future research. Antihelminthic treatment of NC results in disappearance of viable cysts in about one-third of patients with parenchymal disease, but a reduction in seizure recurrence has not been demonstrated in randomized controlled trials. Prevention is critical to reduce the burden of seizure and epilepsy related to NC.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2014000500383&lng=en&tlng=encisticercoseTaenis soliumconvulsãoparasítico
spellingShingle Arturo Carpio
Matthew L. Romo
The relationship between neurocysticercosis and epilepsy: an endless debate
Arquivos de Neuro-Psiquiatria
cisticercose
Taenis solium
convulsão
parasítico
title The relationship between neurocysticercosis and epilepsy: an endless debate
title_full The relationship between neurocysticercosis and epilepsy: an endless debate
title_fullStr The relationship between neurocysticercosis and epilepsy: an endless debate
title_full_unstemmed The relationship between neurocysticercosis and epilepsy: an endless debate
title_short The relationship between neurocysticercosis and epilepsy: an endless debate
title_sort relationship between neurocysticercosis and epilepsy an endless debate
topic cisticercose
Taenis solium
convulsão
parasítico
url http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2014000500383&lng=en&tlng=en
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