Treatment of Febrile Neutropenia and Prophylaxis in Hematologic Malignancies: A Critical Review and Update

Febrile neutropenia is one of the most serious complications in patients with haematological malignancies and chemotherapy. A prompt identification of infection and empirical antibiotic therapy can prolong survival. This paper reviews the guidelines about febrile neutropenia in the setting of hemato...

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Main Authors: Paola Villafuerte-Gutierrez, Lucia Villalon, Juan E. Losa, Cesar Henriquez-Camacho
Format: Article
Language:English
Published: Wiley 2014-01-01
Series:Advances in Hematology
Online Access:http://dx.doi.org/10.1155/2014/986938
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author Paola Villafuerte-Gutierrez
Lucia Villalon
Juan E. Losa
Cesar Henriquez-Camacho
author_facet Paola Villafuerte-Gutierrez
Lucia Villalon
Juan E. Losa
Cesar Henriquez-Camacho
author_sort Paola Villafuerte-Gutierrez
collection DOAJ
description Febrile neutropenia is one of the most serious complications in patients with haematological malignancies and chemotherapy. A prompt identification of infection and empirical antibiotic therapy can prolong survival. This paper reviews the guidelines about febrile neutropenia in the setting of hematologic malignancies, providing an overview of the definition of fever and neutropenia, and categories of risk assessment, management of infections, and prophylaxis.
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institution Kabale University
issn 1687-9104
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language English
publishDate 2014-01-01
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series Advances in Hematology
spelling doaj-art-17ff2fc527524801baa737fd6ed3d2362025-08-20T03:54:21ZengWileyAdvances in Hematology1687-91041687-91122014-01-01201410.1155/2014/986938986938Treatment of Febrile Neutropenia and Prophylaxis in Hematologic Malignancies: A Critical Review and UpdatePaola Villafuerte-Gutierrez0Lucia Villalon1Juan E. Losa2Cesar Henriquez-Camacho3Hospital Universitario Torrejón de Ardoz, Servicio de Hematología, Calle Mateo Inurria, 28850 Madrid, SpainHospital Universitario Fundación Alcorcón, Servicio de Hematología, Calle Budapest 1, 28922 Madrid, SpainUnidad de Medicina Interna, Sección de Enfermedades Infecciosas, Hospital Universitario Fundación Alcorcón, Calle Budapest 1, 28922 Madrid, SpainUnidad de Medicina Interna, Sección de Enfermedades Infecciosas, Hospital Universitario Fundación Alcorcón, Calle Budapest 1, 28922 Madrid, SpainFebrile neutropenia is one of the most serious complications in patients with haematological malignancies and chemotherapy. A prompt identification of infection and empirical antibiotic therapy can prolong survival. This paper reviews the guidelines about febrile neutropenia in the setting of hematologic malignancies, providing an overview of the definition of fever and neutropenia, and categories of risk assessment, management of infections, and prophylaxis.http://dx.doi.org/10.1155/2014/986938
spellingShingle Paola Villafuerte-Gutierrez
Lucia Villalon
Juan E. Losa
Cesar Henriquez-Camacho
Treatment of Febrile Neutropenia and Prophylaxis in Hematologic Malignancies: A Critical Review and Update
Advances in Hematology
title Treatment of Febrile Neutropenia and Prophylaxis in Hematologic Malignancies: A Critical Review and Update
title_full Treatment of Febrile Neutropenia and Prophylaxis in Hematologic Malignancies: A Critical Review and Update
title_fullStr Treatment of Febrile Neutropenia and Prophylaxis in Hematologic Malignancies: A Critical Review and Update
title_full_unstemmed Treatment of Febrile Neutropenia and Prophylaxis in Hematologic Malignancies: A Critical Review and Update
title_short Treatment of Febrile Neutropenia and Prophylaxis in Hematologic Malignancies: A Critical Review and Update
title_sort treatment of febrile neutropenia and prophylaxis in hematologic malignancies a critical review and update
url http://dx.doi.org/10.1155/2014/986938
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AT luciavillalon treatmentoffebrileneutropeniaandprophylaxisinhematologicmalignanciesacriticalreviewandupdate
AT juanelosa treatmentoffebrileneutropeniaandprophylaxisinhematologicmalignanciesacriticalreviewandupdate
AT cesarhenriquezcamacho treatmentoffebrileneutropeniaandprophylaxisinhematologicmalignanciesacriticalreviewandupdate