The research beamlines at the Dresden proton therapy facility: available infrastructure and experimental capabilities
The proton therapy facility in Dresden, Germany, has one treatment room equipped with a rotating gantry where patients are treated and an experimental room equipped with two horizontal beamlines for translational research. The present work describes the technical characteristics and provides measure...
Saved in:
| Main Authors: | , , , , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2025-06-01
|
| Series: | Frontiers in Oncology |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fonc.2025.1594973/full |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1849471341496893440 |
|---|---|
| author | Felix Horst Felix Horst Elisabeth Bodenstein Elisabeth Bodenstein Michael Baumann Michael Baumann Elke Beyreuther Elke Beyreuther Jozef Bokor Wolfgang Enghardt Wolfgang Enghardt Sebastian Gantz Martin Hejzlar Fritz Kurth Markus Meyer Stefan Pieck Stefan Pieck Stefan Pieck Christian Richter Christian Richter Christian Richter Jörg Pawelke Jörg Pawelke |
| author_facet | Felix Horst Felix Horst Elisabeth Bodenstein Elisabeth Bodenstein Michael Baumann Michael Baumann Elke Beyreuther Elke Beyreuther Jozef Bokor Wolfgang Enghardt Wolfgang Enghardt Sebastian Gantz Martin Hejzlar Fritz Kurth Markus Meyer Stefan Pieck Stefan Pieck Stefan Pieck Christian Richter Christian Richter Christian Richter Jörg Pawelke Jörg Pawelke |
| author_sort | Felix Horst |
| collection | DOAJ |
| description | The proton therapy facility in Dresden, Germany, has one treatment room equipped with a rotating gantry where patients are treated and an experimental room equipped with two horizontal beamlines for translational research. The present work describes the technical characteristics and provides measured beam data of these two complementary beamlines, one delivering scanned beams with quasi-clinical parameters and the other one stationary continuous and pulsed pencil beams with parameters exceeding the clinically used range. Features of the facility are the large scale of the experimental room enabling the development and installation of large devices and the parallel beam operation with the clinical room allowing irradiation experiments on weekdays and during daytime. An overview of past and ongoing physics and biology experiments performed at the facility by internal and external researchers from academia and industry is given, demonstrating its versatile experimental capabilities. This includes the development of novel proton therapy approaches and technology as well as elaborate in-vitro and in-vivo small animal experiments for which the necessary infrastructure is available in the same building. |
| format | Article |
| id | doaj-art-17fc9441cf1f4b6f899e52269154436f |
| institution | Kabale University |
| issn | 2234-943X |
| language | English |
| publishDate | 2025-06-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Oncology |
| spelling | doaj-art-17fc9441cf1f4b6f899e52269154436f2025-08-20T03:24:52ZengFrontiers Media S.A.Frontiers in Oncology2234-943X2025-06-011510.3389/fonc.2025.15949731594973The research beamlines at the Dresden proton therapy facility: available infrastructure and experimental capabilitiesFelix Horst0Felix Horst1Elisabeth Bodenstein2Elisabeth Bodenstein3Michael Baumann4Michael Baumann5Elke Beyreuther6Elke Beyreuther7Jozef Bokor8Wolfgang Enghardt9Wolfgang Enghardt10Sebastian Gantz11Martin Hejzlar12Fritz Kurth13Markus Meyer14Stefan Pieck15Stefan Pieck16Stefan Pieck17Christian Richter18Christian Richter19Christian Richter20Jörg Pawelke21Jörg Pawelke22Institute of Radiooncology - OncoRay, Helmholtz-Zentrum Dresden-Rossendorf, Dresden, GermanyOncoRay - National Center for Radiation Research in Oncology, Faculty of Medicine and University Hospital Carl Gustav Carus, Technische Universität Dresden and Helmholtz-Zentrum Dresden-Rossendorf, Dresden, GermanyInstitute of Radiooncology - OncoRay, Helmholtz-Zentrum Dresden-Rossendorf, Dresden, GermanyOncoRay - National Center for Radiation Research in Oncology, Faculty of Medicine and University Hospital Carl Gustav Carus, Technische Universität Dresden and Helmholtz-Zentrum Dresden-Rossendorf, Dresden, GermanyOncoRay - National Center for Radiation Research in Oncology, Faculty of Medicine and University Hospital Carl Gustav Carus, Technische Universität Dresden and Helmholtz-Zentrum Dresden-Rossendorf, Dresden, GermanyDeutsches Krebsforschungszentrum, DKFZ, Heidelberg, GermanyOncoRay - National Center for Radiation Research in Oncology, Faculty of Medicine and University Hospital Carl Gustav Carus, Technische Universität Dresden and Helmholtz-Zentrum Dresden-Rossendorf, Dresden, GermanyInstitute of Radiation Physics, Helmholtz-Zentrum Dresden-Rossendorf, Dresden, GermanyIon Beam Applications (IBA), Louvain-la-Neuve, BelgiumOncoRay - National Center for Radiation Research in Oncology, Faculty of Medicine and University Hospital Carl Gustav Carus, Technische Universität Dresden and Helmholtz-Zentrum Dresden-Rossendorf, Dresden, GermanyDepartment of Radiotherapy and Radiation Oncology, Faculty of Medicine and University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, GermanyOncoRay - National Center for Radiation Research in Oncology, Faculty of Medicine and University Hospital Carl Gustav Carus, Technische Universität Dresden and Helmholtz-Zentrum Dresden-Rossendorf, Dresden, GermanyIon Beam Applications (IBA), Louvain-la-Neuve, BelgiumIon Beam Applications (IBA), Louvain-la-Neuve, BelgiumCentral Department of Research Technology, Helmholtz-Zentrum Dresden-Rossendorf, Dresden, GermanyInstitute of Radiooncology - OncoRay, Helmholtz-Zentrum Dresden-Rossendorf, Dresden, GermanyOncoRay - National Center for Radiation Research in Oncology, Faculty of Medicine and University Hospital Carl Gustav Carus, Technische Universität Dresden and Helmholtz-Zentrum Dresden-Rossendorf, Dresden, GermanyDepartment of Radiotherapy and Radiation Oncology, Faculty of Medicine and University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, GermanyInstitute of Radiooncology - OncoRay, Helmholtz-Zentrum Dresden-Rossendorf, Dresden, GermanyOncoRay - National Center for Radiation Research in Oncology, Faculty of Medicine and University Hospital Carl Gustav Carus, Technische Universität Dresden and Helmholtz-Zentrum Dresden-Rossendorf, Dresden, GermanyDepartment of Radiotherapy and Radiation Oncology, Faculty of Medicine and University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, GermanyInstitute of Radiooncology - OncoRay, Helmholtz-Zentrum Dresden-Rossendorf, Dresden, GermanyOncoRay - National Center for Radiation Research in Oncology, Faculty of Medicine and University Hospital Carl Gustav Carus, Technische Universität Dresden and Helmholtz-Zentrum Dresden-Rossendorf, Dresden, GermanyThe proton therapy facility in Dresden, Germany, has one treatment room equipped with a rotating gantry where patients are treated and an experimental room equipped with two horizontal beamlines for translational research. The present work describes the technical characteristics and provides measured beam data of these two complementary beamlines, one delivering scanned beams with quasi-clinical parameters and the other one stationary continuous and pulsed pencil beams with parameters exceeding the clinically used range. Features of the facility are the large scale of the experimental room enabling the development and installation of large devices and the parallel beam operation with the clinical room allowing irradiation experiments on weekdays and during daytime. An overview of past and ongoing physics and biology experiments performed at the facility by internal and external researchers from academia and industry is given, demonstrating its versatile experimental capabilities. This includes the development of novel proton therapy approaches and technology as well as elaborate in-vitro and in-vivo small animal experiments for which the necessary infrastructure is available in the same building.https://www.frontiersin.org/articles/10.3389/fonc.2025.1594973/fullproton therapyexperimental roombeamlinetranslational researchproton beam |
| spellingShingle | Felix Horst Felix Horst Elisabeth Bodenstein Elisabeth Bodenstein Michael Baumann Michael Baumann Elke Beyreuther Elke Beyreuther Jozef Bokor Wolfgang Enghardt Wolfgang Enghardt Sebastian Gantz Martin Hejzlar Fritz Kurth Markus Meyer Stefan Pieck Stefan Pieck Stefan Pieck Christian Richter Christian Richter Christian Richter Jörg Pawelke Jörg Pawelke The research beamlines at the Dresden proton therapy facility: available infrastructure and experimental capabilities Frontiers in Oncology proton therapy experimental room beamline translational research proton beam |
| title | The research beamlines at the Dresden proton therapy facility: available infrastructure and experimental capabilities |
| title_full | The research beamlines at the Dresden proton therapy facility: available infrastructure and experimental capabilities |
| title_fullStr | The research beamlines at the Dresden proton therapy facility: available infrastructure and experimental capabilities |
| title_full_unstemmed | The research beamlines at the Dresden proton therapy facility: available infrastructure and experimental capabilities |
| title_short | The research beamlines at the Dresden proton therapy facility: available infrastructure and experimental capabilities |
| title_sort | research beamlines at the dresden proton therapy facility available infrastructure and experimental capabilities |
| topic | proton therapy experimental room beamline translational research proton beam |
| url | https://www.frontiersin.org/articles/10.3389/fonc.2025.1594973/full |
| work_keys_str_mv | AT felixhorst theresearchbeamlinesatthedresdenprotontherapyfacilityavailableinfrastructureandexperimentalcapabilities AT felixhorst theresearchbeamlinesatthedresdenprotontherapyfacilityavailableinfrastructureandexperimentalcapabilities AT elisabethbodenstein theresearchbeamlinesatthedresdenprotontherapyfacilityavailableinfrastructureandexperimentalcapabilities AT elisabethbodenstein theresearchbeamlinesatthedresdenprotontherapyfacilityavailableinfrastructureandexperimentalcapabilities AT michaelbaumann theresearchbeamlinesatthedresdenprotontherapyfacilityavailableinfrastructureandexperimentalcapabilities AT michaelbaumann theresearchbeamlinesatthedresdenprotontherapyfacilityavailableinfrastructureandexperimentalcapabilities AT elkebeyreuther theresearchbeamlinesatthedresdenprotontherapyfacilityavailableinfrastructureandexperimentalcapabilities AT elkebeyreuther theresearchbeamlinesatthedresdenprotontherapyfacilityavailableinfrastructureandexperimentalcapabilities AT jozefbokor theresearchbeamlinesatthedresdenprotontherapyfacilityavailableinfrastructureandexperimentalcapabilities AT wolfgangenghardt theresearchbeamlinesatthedresdenprotontherapyfacilityavailableinfrastructureandexperimentalcapabilities AT wolfgangenghardt theresearchbeamlinesatthedresdenprotontherapyfacilityavailableinfrastructureandexperimentalcapabilities AT sebastiangantz theresearchbeamlinesatthedresdenprotontherapyfacilityavailableinfrastructureandexperimentalcapabilities AT martinhejzlar theresearchbeamlinesatthedresdenprotontherapyfacilityavailableinfrastructureandexperimentalcapabilities AT fritzkurth theresearchbeamlinesatthedresdenprotontherapyfacilityavailableinfrastructureandexperimentalcapabilities AT markusmeyer theresearchbeamlinesatthedresdenprotontherapyfacilityavailableinfrastructureandexperimentalcapabilities AT stefanpieck theresearchbeamlinesatthedresdenprotontherapyfacilityavailableinfrastructureandexperimentalcapabilities AT stefanpieck theresearchbeamlinesatthedresdenprotontherapyfacilityavailableinfrastructureandexperimentalcapabilities AT stefanpieck theresearchbeamlinesatthedresdenprotontherapyfacilityavailableinfrastructureandexperimentalcapabilities AT christianrichter theresearchbeamlinesatthedresdenprotontherapyfacilityavailableinfrastructureandexperimentalcapabilities AT christianrichter theresearchbeamlinesatthedresdenprotontherapyfacilityavailableinfrastructureandexperimentalcapabilities AT christianrichter theresearchbeamlinesatthedresdenprotontherapyfacilityavailableinfrastructureandexperimentalcapabilities AT jorgpawelke theresearchbeamlinesatthedresdenprotontherapyfacilityavailableinfrastructureandexperimentalcapabilities AT jorgpawelke theresearchbeamlinesatthedresdenprotontherapyfacilityavailableinfrastructureandexperimentalcapabilities AT felixhorst researchbeamlinesatthedresdenprotontherapyfacilityavailableinfrastructureandexperimentalcapabilities AT felixhorst researchbeamlinesatthedresdenprotontherapyfacilityavailableinfrastructureandexperimentalcapabilities AT elisabethbodenstein researchbeamlinesatthedresdenprotontherapyfacilityavailableinfrastructureandexperimentalcapabilities AT elisabethbodenstein researchbeamlinesatthedresdenprotontherapyfacilityavailableinfrastructureandexperimentalcapabilities AT michaelbaumann researchbeamlinesatthedresdenprotontherapyfacilityavailableinfrastructureandexperimentalcapabilities AT michaelbaumann researchbeamlinesatthedresdenprotontherapyfacilityavailableinfrastructureandexperimentalcapabilities AT elkebeyreuther researchbeamlinesatthedresdenprotontherapyfacilityavailableinfrastructureandexperimentalcapabilities AT elkebeyreuther researchbeamlinesatthedresdenprotontherapyfacilityavailableinfrastructureandexperimentalcapabilities AT jozefbokor researchbeamlinesatthedresdenprotontherapyfacilityavailableinfrastructureandexperimentalcapabilities AT wolfgangenghardt researchbeamlinesatthedresdenprotontherapyfacilityavailableinfrastructureandexperimentalcapabilities AT wolfgangenghardt researchbeamlinesatthedresdenprotontherapyfacilityavailableinfrastructureandexperimentalcapabilities AT sebastiangantz researchbeamlinesatthedresdenprotontherapyfacilityavailableinfrastructureandexperimentalcapabilities AT martinhejzlar researchbeamlinesatthedresdenprotontherapyfacilityavailableinfrastructureandexperimentalcapabilities AT fritzkurth researchbeamlinesatthedresdenprotontherapyfacilityavailableinfrastructureandexperimentalcapabilities AT markusmeyer researchbeamlinesatthedresdenprotontherapyfacilityavailableinfrastructureandexperimentalcapabilities AT stefanpieck researchbeamlinesatthedresdenprotontherapyfacilityavailableinfrastructureandexperimentalcapabilities AT stefanpieck researchbeamlinesatthedresdenprotontherapyfacilityavailableinfrastructureandexperimentalcapabilities AT stefanpieck researchbeamlinesatthedresdenprotontherapyfacilityavailableinfrastructureandexperimentalcapabilities AT christianrichter researchbeamlinesatthedresdenprotontherapyfacilityavailableinfrastructureandexperimentalcapabilities AT christianrichter researchbeamlinesatthedresdenprotontherapyfacilityavailableinfrastructureandexperimentalcapabilities AT christianrichter researchbeamlinesatthedresdenprotontherapyfacilityavailableinfrastructureandexperimentalcapabilities AT jorgpawelke researchbeamlinesatthedresdenprotontherapyfacilityavailableinfrastructureandexperimentalcapabilities AT jorgpawelke researchbeamlinesatthedresdenprotontherapyfacilityavailableinfrastructureandexperimentalcapabilities |