Herb5GluCon: A novel polyherbal formulation with dual-action inhibiting properties against oxidative stress and glycoside hydrolases – an in silico and in vitro approach

Herb5GluCon: A novel polyherbal formulation with dual-action inhibiting properties against oxidative stress and glycoside hydrolases – an in silico and in vitro approach

Introduction: Oxidative stress contributes to hyperglycaemia by inducing the hyperactivity of alpha-amylase (AA) and alpha-glucosidase (AG) enzymes. The study aimed to evaluate the antioxidant and anti-glycoside hydrolase potential of a novel polyherbal formulation (Herb5GluCon) and identify its phy...

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Main Authors: Abbirami Balachandran, Patrick N. Okechukwu, Baskaran Gunasekaran, Jeleń Małgorzata, Beata Morak-Młodawska, Gabriele R.A. Froemming, Sameer Sapra, Charlie A. Lavilla, Jr., Merell P. Billacura, Salini D. Rajendran, Anis Najwa Abdul Rani, Anand Gaurav
Format: Article
Language:English
Published: Elsevier 2025-02-01
Series:Phytomedicine Plus
Subjects:
Polyherbal formulation
Mass spectrometry
Antioxidant
Anti-glycoside hydrolase
Oxidative stress
Hyperglycaemia
Online Access:http://www.sciencedirect.com/science/article/pii/S2667031324001908
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