Esophageal Rupture as a Primary Manifestation in Eosinophilic Esophagitis
Eosinophilic esophagitis (EoE) is a chronic inflammatory process characterized by symptoms of esophageal dysfunction and, histologically, by eosinophilic infiltration of the esophagus. In adults, it commonly presents with dysphagia, food impaction, and chest or abdominal pain. Chronic inflammation c...
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| Language: | English |
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Wiley
2014-01-01
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| Series: | Case Reports in Medicine |
| Online Access: | http://dx.doi.org/10.1155/2014/673189 |
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| author | Natalia Vernon Divyanshu Mohananey Ehsan Ghetmiri Gisoo Ghaffari |
| author_facet | Natalia Vernon Divyanshu Mohananey Ehsan Ghetmiri Gisoo Ghaffari |
| author_sort | Natalia Vernon |
| collection | DOAJ |
| description | Eosinophilic esophagitis (EoE) is a chronic inflammatory process characterized by symptoms of esophageal dysfunction and, histologically, by eosinophilic infiltration of the esophagus. In adults, it commonly presents with dysphagia, food impaction, and chest or abdominal pain. Chronic inflammation can lead to diffuse narrowing of the esophageal lumen which may cause food impaction. Endoscopic procedures to relieve food impaction may lead to complications such as esophageal perforation due to the friability of the esophageal mucosa. Spontaneous transmural esophageal rupture, also known as Boerhaave’s syndrome, as a primary manifestation of EoE is rare. In this paper, we present two adult patients who presented with esophageal perforation as the initial manifestation of EoE. This rare complication of EoE has been documented in 13 other reports (11 adults, 2 children) and only 1 of the patients had been previously diagnosed with EoE. A history of dysphagia was present in 1 of our patients and in the majority of previously documented patients. Esophageal perforation is a potentially severe complication of EoE. Patients with a history of dysphagia and patients with spontaneous esophageal perforation should warrant an evaluation for EoE. |
| format | Article |
| id | doaj-art-17f8066dd1c549e386427c4270b7474c |
| institution | Kabale University |
| issn | 1687-9627 1687-9635 |
| language | English |
| publishDate | 2014-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Medicine |
| spelling | doaj-art-17f8066dd1c549e386427c4270b7474c2025-02-03T05:46:07ZengWileyCase Reports in Medicine1687-96271687-96352014-01-01201410.1155/2014/673189673189Esophageal Rupture as a Primary Manifestation in Eosinophilic EsophagitisNatalia Vernon0Divyanshu Mohananey1Ehsan Ghetmiri2Gisoo Ghaffari3Penn State Hershey Medical Center, 500 University Drive, MC H041, Hershey, PA 17033, USAPenn State Hershey Medical Center, 500 University Drive, MC H041, Hershey, PA 17033, USAPenn State Hershey Medical Center, 500 University Drive, MC H041, Hershey, PA 17033, USAPenn State Hershey Medical Center, 500 University Drive, MC H041, Hershey, PA 17033, USAEosinophilic esophagitis (EoE) is a chronic inflammatory process characterized by symptoms of esophageal dysfunction and, histologically, by eosinophilic infiltration of the esophagus. In adults, it commonly presents with dysphagia, food impaction, and chest or abdominal pain. Chronic inflammation can lead to diffuse narrowing of the esophageal lumen which may cause food impaction. Endoscopic procedures to relieve food impaction may lead to complications such as esophageal perforation due to the friability of the esophageal mucosa. Spontaneous transmural esophageal rupture, also known as Boerhaave’s syndrome, as a primary manifestation of EoE is rare. In this paper, we present two adult patients who presented with esophageal perforation as the initial manifestation of EoE. This rare complication of EoE has been documented in 13 other reports (11 adults, 2 children) and only 1 of the patients had been previously diagnosed with EoE. A history of dysphagia was present in 1 of our patients and in the majority of previously documented patients. Esophageal perforation is a potentially severe complication of EoE. Patients with a history of dysphagia and patients with spontaneous esophageal perforation should warrant an evaluation for EoE.http://dx.doi.org/10.1155/2014/673189 |
| spellingShingle | Natalia Vernon Divyanshu Mohananey Ehsan Ghetmiri Gisoo Ghaffari Esophageal Rupture as a Primary Manifestation in Eosinophilic Esophagitis Case Reports in Medicine |
| title | Esophageal Rupture as a Primary Manifestation in Eosinophilic Esophagitis |
| title_full | Esophageal Rupture as a Primary Manifestation in Eosinophilic Esophagitis |
| title_fullStr | Esophageal Rupture as a Primary Manifestation in Eosinophilic Esophagitis |
| title_full_unstemmed | Esophageal Rupture as a Primary Manifestation in Eosinophilic Esophagitis |
| title_short | Esophageal Rupture as a Primary Manifestation in Eosinophilic Esophagitis |
| title_sort | esophageal rupture as a primary manifestation in eosinophilic esophagitis |
| url | http://dx.doi.org/10.1155/2014/673189 |
| work_keys_str_mv | AT nataliavernon esophagealruptureasaprimarymanifestationineosinophilicesophagitis AT divyanshumohananey esophagealruptureasaprimarymanifestationineosinophilicesophagitis AT ehsanghetmiri esophagealruptureasaprimarymanifestationineosinophilicesophagitis AT gisooghaffari esophagealruptureasaprimarymanifestationineosinophilicesophagitis |