Alterations in apoptotic pathways and expression of miR-134, miR-181, and miR-497 induced by Wharton’s jelly-derived mesenchymal stem cells in a rat model of ischemic brain injury

Alterations in apoptotic pathways and expression of miR-134, miR-181, and miR-497 induced by Wharton’s jelly-derived mesenchymal stem cells in a rat model of ischemic brain injury

Background: MicroRNAs (miRNAs) play crucial roles in regulating cell survival and signaling pathways. Mesenchymal stem cells (MSCs), particularly those derived from Wharton’s Jelly (WJ-MSCs), have shown potential in promoting cell survival and reducing apoptosis. This study evaluates the effects of...

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Bibliographic Details
Main Authors: Tahereh Alizamir, Ali Fathi Jouzdani, Fatemeh Attari, Leila Arab, Zeinab Ashaari, Alireza Komaki, Gholamreza Hassanzadeh
Format: Article
Language:English
Published: Elsevier 2025-06-01
Series:IBRO Neuroscience Reports
Subjects:
Apoptotic
Ischemia
Mesenchymal stem cells
MicroRNA
Neuroprotective
Wharton's jelly cells
Online Access:http://www.sciencedirect.com/science/article/pii/S2667242125000636
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