Efficacy and safety of tranexamic acid administration for subarachnoid hemorrhage: a systematic review and meta-analysis

Efficacy and safety of tranexamic acid administration for subarachnoid hemorrhage: a systematic review and meta-analysis

IntroductionAneurysmal subarachnoid hemorrhage (SAH) carries a high risk of early rebleeding and worsens prognosis. Tranexamic acid (TXA), an antifibrinolytic agent, can prevent rebleeding; however, its effects on mortality and neurological outcomes remain controversial.MethodsThis review evaluated...

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Main Authors: Eriya Imai, Hiroshi Ito, Hiromu Okano, Akihiko Inoue, Takero Terayama, Hiroshi Okamoto, Toru Hifumi, Yoshihisa Fujimoto, Gaku Fujiwara, Yasuhiro Kuroda
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-06-01
Series:Frontiers in Neurology
Subjects:
meta-analysis
subarachnoid hemorrhage
systematic review
tranexamic acid
rebleeding
Online Access:https://www.frontiersin.org/articles/10.3389/fneur.2025.1617817/full
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