Assessment of quality in volatile oil from three basic sources of Xinyi from Hubei by anatomy, GC-MS, and chemometric methods

Abstract “Xinyi” (Magnolia biondii Pampan., Magnolia denudata Desr., and Magnolia sprengeri Pampan.) is a traditional Chinese medicine listed in the Pharmacopoeia of the People’s Republic of China. “Xinyi” has anti-inflammatory, anti-allergic, antioxidant, and antibacterial effects, and has signific...

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Main Authors: Xiaopei Wu, Wei Yin, Yanqun Li, Hui Wu, Qiqing Cheng, Qiang He, Hong Wu, Mingli Hu
Format: Article
Language:English
Published: Nature Portfolio 2025-02-01
Series:Scientific Reports
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Online Access:https://doi.org/10.1038/s41598-025-91477-z
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author Xiaopei Wu
Wei Yin
Yanqun Li
Hui Wu
Qiqing Cheng
Qiang He
Hong Wu
Mingli Hu
author_facet Xiaopei Wu
Wei Yin
Yanqun Li
Hui Wu
Qiqing Cheng
Qiang He
Hong Wu
Mingli Hu
author_sort Xiaopei Wu
collection DOAJ
description Abstract “Xinyi” (Magnolia biondii Pampan., Magnolia denudata Desr., and Magnolia sprengeri Pampan.) is a traditional Chinese medicine listed in the Pharmacopoeia of the People’s Republic of China. “Xinyi” has anti-inflammatory, anti-allergic, antioxidant, and antibacterial effects, and has significant curative effects in the treatment of acute and chronic rhinitis, allergic rhinitis, and other rhinitis symptoms. However, comparative quality assessments of these three species are scarce. This study investigated the variations in the volatile oil content and composition in the flower buds of M. biondii, M. denudata, and M. sprengeri using the gas chromatography–mass spectrometry (GC–MS) and the microscopic analysis at different growth stages. This study indicated the following findings. (1) The volatile oil levels varied among the species, with M. biondii, M. denudata, and M. sprengeri peaking, respectively. In addition, the cell density was positively correlated with the oil deposition. (2) The content of 1,8-Cineole varied significantly, where M. biondii exhibited the high levels at 14.50% at stage 4 and 16.40% at stage 5; M. denudata peaked at 17.87% at stage 5; and M. sprengeri was 1.07% at stage 3. Moreover, M. biondii and M. denudata from Hubei exceeded the Pharmacopoeia’s 1% standard, whereas M. sprengeri did not. These findings underscore the need to improve the herb production standards and provide valuable data for assessing the therapeutic potential of these “Xinyi” species.
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spelling doaj-art-17e369dfd1f34a7684d9bb0b581851602025-08-20T02:16:40ZengNature PortfolioScientific Reports2045-23222025-02-0115111510.1038/s41598-025-91477-zAssessment of quality in volatile oil from three basic sources of Xinyi from Hubei by anatomy, GC-MS, and chemometric methodsXiaopei Wu0Wei Yin1Yanqun Li2Hui Wu3Qiqing Cheng4Qiang He5Hong Wu6Mingli Hu7School of Pharmacy, Hubei University of Science and TechnologyGenolmmune Therapeutics co., LtdMedicinal Plant Research Center, College of Life Sciences, South China Agricultural UniversityXianning Public Inspection Center of Hubei ProvinceSchool of Pharmacy, Hubei University of Science and TechnologyXianning Public Inspection Center of Hubei ProvinceMedicinal Plant Research Center, College of Life Sciences, South China Agricultural UniversitySchool of Pharmacy, Hubei University of Science and TechnologyAbstract “Xinyi” (Magnolia biondii Pampan., Magnolia denudata Desr., and Magnolia sprengeri Pampan.) is a traditional Chinese medicine listed in the Pharmacopoeia of the People’s Republic of China. “Xinyi” has anti-inflammatory, anti-allergic, antioxidant, and antibacterial effects, and has significant curative effects in the treatment of acute and chronic rhinitis, allergic rhinitis, and other rhinitis symptoms. However, comparative quality assessments of these three species are scarce. This study investigated the variations in the volatile oil content and composition in the flower buds of M. biondii, M. denudata, and M. sprengeri using the gas chromatography–mass spectrometry (GC–MS) and the microscopic analysis at different growth stages. This study indicated the following findings. (1) The volatile oil levels varied among the species, with M. biondii, M. denudata, and M. sprengeri peaking, respectively. In addition, the cell density was positively correlated with the oil deposition. (2) The content of 1,8-Cineole varied significantly, where M. biondii exhibited the high levels at 14.50% at stage 4 and 16.40% at stage 5; M. denudata peaked at 17.87% at stage 5; and M. sprengeri was 1.07% at stage 3. Moreover, M. biondii and M. denudata from Hubei exceeded the Pharmacopoeia’s 1% standard, whereas M. sprengeri did not. These findings underscore the need to improve the herb production standards and provide valuable data for assessing the therapeutic potential of these “Xinyi” species.https://doi.org/10.1038/s41598-025-91477-zMagnolia biondii Pampan.Magnolia denudata Desr.Magnolia sprengeri Pampan.Oil cellVolatile oilGC-MS
spellingShingle Xiaopei Wu
Wei Yin
Yanqun Li
Hui Wu
Qiqing Cheng
Qiang He
Hong Wu
Mingli Hu
Assessment of quality in volatile oil from three basic sources of Xinyi from Hubei by anatomy, GC-MS, and chemometric methods
Scientific Reports
Magnolia biondii Pampan.
Magnolia denudata Desr.
Magnolia sprengeri Pampan.
Oil cell
Volatile oil
GC-MS
title Assessment of quality in volatile oil from three basic sources of Xinyi from Hubei by anatomy, GC-MS, and chemometric methods
title_full Assessment of quality in volatile oil from three basic sources of Xinyi from Hubei by anatomy, GC-MS, and chemometric methods
title_fullStr Assessment of quality in volatile oil from three basic sources of Xinyi from Hubei by anatomy, GC-MS, and chemometric methods
title_full_unstemmed Assessment of quality in volatile oil from three basic sources of Xinyi from Hubei by anatomy, GC-MS, and chemometric methods
title_short Assessment of quality in volatile oil from three basic sources of Xinyi from Hubei by anatomy, GC-MS, and chemometric methods
title_sort assessment of quality in volatile oil from three basic sources of xinyi from hubei by anatomy gc ms and chemometric methods
topic Magnolia biondii Pampan.
Magnolia denudata Desr.
Magnolia sprengeri Pampan.
Oil cell
Volatile oil
GC-MS
url https://doi.org/10.1038/s41598-025-91477-z
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