Plurihormonal Cosecretion by a Case of Adrenocortical Oncocytic Neoplasm
Adrenocortical oncocytic neoplasms (oncocytomas) are extremely rare; only approximately 159 cases have been described so far. The majority are nonfunctional and benign. We describe an unusual case of a functional oncocytoma secreting an excess of glucocorticoids (cortisol) and androgens (androstened...
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| Format: | Article |
| Language: | English |
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Wiley
2016-01-01
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| Series: | Case Reports in Endocrinology |
| Online Access: | http://dx.doi.org/10.1155/2016/6785925 |
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| author | J. J. Corrales C. Robles-Lázaro A. I. Sánchez-Marcos M. C. González-Sánchez P. Antúnez-Plaza J. M. Miralles |
| author_facet | J. J. Corrales C. Robles-Lázaro A. I. Sánchez-Marcos M. C. González-Sánchez P. Antúnez-Plaza J. M. Miralles |
| author_sort | J. J. Corrales |
| collection | DOAJ |
| description | Adrenocortical oncocytic neoplasms (oncocytomas) are extremely rare; only approximately 159 cases have been described so far. The majority are nonfunctional and benign. We describe an unusual case of a functional oncocytoma secreting an excess of glucocorticoids (cortisol) and androgens (androstenedione and DHEAS), a pattern of plurihormonal cosecretion previously not reported in men, presenting with endocrine manifestations of Cushing’s syndrome. The neoplasm was considered to be of uncertain malignant potential (borderline) according to the Lin-Weiss-Bisceglia criteria. |
| format | Article |
| id | doaj-art-17df62f2a5a7437eb6a6d84fc3cdbad8 |
| institution | Kabale University |
| issn | 2090-6501 2090-651X |
| language | English |
| publishDate | 2016-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Endocrinology |
| spelling | doaj-art-17df62f2a5a7437eb6a6d84fc3cdbad82025-02-03T05:47:31ZengWileyCase Reports in Endocrinology2090-65012090-651X2016-01-01201610.1155/2016/67859256785925Plurihormonal Cosecretion by a Case of Adrenocortical Oncocytic NeoplasmJ. J. Corrales0C. Robles-Lázaro1A. I. Sánchez-Marcos2M. C. González-Sánchez3P. Antúnez-Plaza4J. M. Miralles5Servicio de Endocrinología y Nutrición, Hospital Clínico Universitario, Paseo de San Vicente No. 58, 37007 Salamanca, SpainServicio de Endocrinología y Nutrición, Hospital Clínico Universitario, Paseo de San Vicente No. 58, 37007 Salamanca, SpainServicio de Endocrinología y Nutrición, Hospital Clínico Universitario, Paseo de San Vicente No. 58, 37007 Salamanca, SpainUnidad de Cirugía Endocrina, Departamento de Cirugía, Hospital Clínico Universitario de Salamanca, Paseo de San Vicente No. 58, 37007 Salamanca, SpainServicio de Anatomía Patológica, Departamento de Anatomía Patológica, Hospital Universitario de Salamanca, Paseo de San Vicente No. 58, 37007 Salamanca, SpainServicio de Endocrinología y Nutrición, Hospital Clínico Universitario, Paseo de San Vicente No. 58, 37007 Salamanca, SpainAdrenocortical oncocytic neoplasms (oncocytomas) are extremely rare; only approximately 159 cases have been described so far. The majority are nonfunctional and benign. We describe an unusual case of a functional oncocytoma secreting an excess of glucocorticoids (cortisol) and androgens (androstenedione and DHEAS), a pattern of plurihormonal cosecretion previously not reported in men, presenting with endocrine manifestations of Cushing’s syndrome. The neoplasm was considered to be of uncertain malignant potential (borderline) according to the Lin-Weiss-Bisceglia criteria.http://dx.doi.org/10.1155/2016/6785925 |
| spellingShingle | J. J. Corrales C. Robles-Lázaro A. I. Sánchez-Marcos M. C. González-Sánchez P. Antúnez-Plaza J. M. Miralles Plurihormonal Cosecretion by a Case of Adrenocortical Oncocytic Neoplasm Case Reports in Endocrinology |
| title | Plurihormonal Cosecretion by a Case of Adrenocortical Oncocytic Neoplasm |
| title_full | Plurihormonal Cosecretion by a Case of Adrenocortical Oncocytic Neoplasm |
| title_fullStr | Plurihormonal Cosecretion by a Case of Adrenocortical Oncocytic Neoplasm |
| title_full_unstemmed | Plurihormonal Cosecretion by a Case of Adrenocortical Oncocytic Neoplasm |
| title_short | Plurihormonal Cosecretion by a Case of Adrenocortical Oncocytic Neoplasm |
| title_sort | plurihormonal cosecretion by a case of adrenocortical oncocytic neoplasm |
| url | http://dx.doi.org/10.1155/2016/6785925 |
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