Diabetic Bone Disease and Diabetic Myopathy: Manifestations of the Impaired Muscle-Bone Unit in Type 1 Diabetes

Type 1 diabetes is associated with complications affecting muscle and bone, with diabetic bone disease and diabetic myopathy becoming increasingly reported in the past few decades. This review is aimed at succinctly reviewing the literature on the current knowledge regarding these increasingly ident...

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Main Authors: Callie Travis, Priya S. Srivastava, Thomas J. Hawke, Evangelia Kalaitzoglou
Format: Article
Language:English
Published: Wiley 2022-01-01
Series:Journal of Diabetes Research
Online Access:http://dx.doi.org/10.1155/2022/2650342
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author Callie Travis
Priya S. Srivastava
Thomas J. Hawke
Evangelia Kalaitzoglou
author_facet Callie Travis
Priya S. Srivastava
Thomas J. Hawke
Evangelia Kalaitzoglou
author_sort Callie Travis
collection DOAJ
description Type 1 diabetes is associated with complications affecting muscle and bone, with diabetic bone disease and diabetic myopathy becoming increasingly reported in the past few decades. This review is aimed at succinctly reviewing the literature on the current knowledge regarding these increasingly identified and possibly interconnected complications on the musculoskeletal system. Furthermore, this review summarizes several nonmechanical factors that could be mediating the development and progression of premature musculoskeletal decline in this population and discusses preventative measures to reduce the burden of diabetes on the musculoskeletal system.
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publishDate 2022-01-01
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series Journal of Diabetes Research
spelling doaj-art-17dd8cf2c8644ac28eccaf7a674c0ae02025-08-20T02:02:29ZengWileyJournal of Diabetes Research2314-67532022-01-01202210.1155/2022/2650342Diabetic Bone Disease and Diabetic Myopathy: Manifestations of the Impaired Muscle-Bone Unit in Type 1 DiabetesCallie Travis0Priya S. Srivastava1Thomas J. Hawke2Evangelia Kalaitzoglou3University of Kentucky College of MedicineDepartment of PediatricsDepartment of Pathology and Molecular MedicineUniversity of KentuckyType 1 diabetes is associated with complications affecting muscle and bone, with diabetic bone disease and diabetic myopathy becoming increasingly reported in the past few decades. This review is aimed at succinctly reviewing the literature on the current knowledge regarding these increasingly identified and possibly interconnected complications on the musculoskeletal system. Furthermore, this review summarizes several nonmechanical factors that could be mediating the development and progression of premature musculoskeletal decline in this population and discusses preventative measures to reduce the burden of diabetes on the musculoskeletal system.http://dx.doi.org/10.1155/2022/2650342
spellingShingle Callie Travis
Priya S. Srivastava
Thomas J. Hawke
Evangelia Kalaitzoglou
Diabetic Bone Disease and Diabetic Myopathy: Manifestations of the Impaired Muscle-Bone Unit in Type 1 Diabetes
Journal of Diabetes Research
title Diabetic Bone Disease and Diabetic Myopathy: Manifestations of the Impaired Muscle-Bone Unit in Type 1 Diabetes
title_full Diabetic Bone Disease and Diabetic Myopathy: Manifestations of the Impaired Muscle-Bone Unit in Type 1 Diabetes
title_fullStr Diabetic Bone Disease and Diabetic Myopathy: Manifestations of the Impaired Muscle-Bone Unit in Type 1 Diabetes
title_full_unstemmed Diabetic Bone Disease and Diabetic Myopathy: Manifestations of the Impaired Muscle-Bone Unit in Type 1 Diabetes
title_short Diabetic Bone Disease and Diabetic Myopathy: Manifestations of the Impaired Muscle-Bone Unit in Type 1 Diabetes
title_sort diabetic bone disease and diabetic myopathy manifestations of the impaired muscle bone unit in type 1 diabetes
url http://dx.doi.org/10.1155/2022/2650342
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AT thomasjhawke diabeticbonediseaseanddiabeticmyopathymanifestationsoftheimpairedmuscleboneunitintype1diabetes
AT evangeliakalaitzoglou diabeticbonediseaseanddiabeticmyopathymanifestationsoftheimpairedmuscleboneunitintype1diabetes