Albumin-Based Nanoparticles with Factorial Design as a Promising Approach for Remodeled Repaglinide: Evidence from In Silico, In Vitro, and In Vivo Evaluations

Albumin-Based Nanoparticles with Factorial Design as a Promising Approach for Remodeled Repaglinide: Evidence from In Silico, In Vitro, and In Vivo Evaluations

<b>Background/Objectives:</b> Hyperlipidemia is a silent threat lurking in the bloodstream of millions worldwide. The nano-based platform has emerged as a promising drug delivery technology. Repaglinide, an anti-diabetic drug, was investigated recently as an antihyperlipidemic candidate...

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Main Authors: Mennatullah M. Faisal, Eman Gomaa, Mohamed S. Attia, Rana M. Abdelnaby, Adel Ehab Ibrahim, Ahmed Al-Harrasi, Sami El Deeb, Al Zahraa G. Al Ashmawy
Format: Article
Language:English
Published: MDPI AG 2025-03-01
Series:Pharmaceutics
Subjects:
factorial design
atherosclerosis
albumin
nanoparticles
in silico
triglycerides
Online Access:https://www.mdpi.com/1999-4923/17/3/350
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