An overview of RNA virus-encoded microRNAs

Abstract MicroRNAs (miRNAs) are a number of small non-coding RNAs playing a regulatory part in gene expression. Many virus-encoded miRNAs have been found, which manifests that viruses as well apply the basic pattern of gene regulation, however, mostly in viruses transcribed from double-stranded DNA...

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Main Authors: Xihan Li, Xiaoping Zou
Format: Article
Language:English
Published: ELS Publishing (ELSP) 2019-10-01
Series:ExRNA
Online Access:http://link.springer.com/article/10.1186/s41544-019-0037-6
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author Xihan Li
Xiaoping Zou
author_facet Xihan Li
Xiaoping Zou
author_sort Xihan Li
collection DOAJ
description Abstract MicroRNAs (miRNAs) are a number of small non-coding RNAs playing a regulatory part in gene expression. Many virus-encoded miRNAs have been found, which manifests that viruses as well apply the basic pattern of gene regulation, however, mostly in viruses transcribed from double-stranded DNA genomes. It is still in dispute if RNA viruses could encode miRNAs because the excision of miRNA might result in the cleavage of viral RNA genome. We will focus on the miRNAs encoded by RNA virus and discuss their potential role in viral replication cycle and host cells.
format Article
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institution DOAJ
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publishDate 2019-10-01
publisher ELS Publishing (ELSP)
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series ExRNA
spelling doaj-art-17cd0a258ac9408e8aef78b88a8809dd2025-08-20T02:53:07ZengELS Publishing (ELSP)ExRNA2398-00602019-10-01111510.1186/s41544-019-0037-6An overview of RNA virus-encoded microRNAsXihan Li0Xiaoping Zou1Department of Gastroenterology, Affiliated Drum Tower Hospital, Nanjing University School of MedicineDepartment of Gastroenterology, Affiliated Drum Tower Hospital, Nanjing University School of MedicineAbstract MicroRNAs (miRNAs) are a number of small non-coding RNAs playing a regulatory part in gene expression. Many virus-encoded miRNAs have been found, which manifests that viruses as well apply the basic pattern of gene regulation, however, mostly in viruses transcribed from double-stranded DNA genomes. It is still in dispute if RNA viruses could encode miRNAs because the excision of miRNA might result in the cleavage of viral RNA genome. We will focus on the miRNAs encoded by RNA virus and discuss their potential role in viral replication cycle and host cells.http://link.springer.com/article/10.1186/s41544-019-0037-6
spellingShingle Xihan Li
Xiaoping Zou
An overview of RNA virus-encoded microRNAs
ExRNA
title An overview of RNA virus-encoded microRNAs
title_full An overview of RNA virus-encoded microRNAs
title_fullStr An overview of RNA virus-encoded microRNAs
title_full_unstemmed An overview of RNA virus-encoded microRNAs
title_short An overview of RNA virus-encoded microRNAs
title_sort overview of rna virus encoded micrornas
url http://link.springer.com/article/10.1186/s41544-019-0037-6
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