Bilateral Severe Sterile Inflammation with Hypopyon after Simultaneous Intravitreal Triamcinolone Acetonide and Aflibercept Injection in a Patient with Bilateral Marked Rubeosis Associated with Ocular Ischemic Syndrome
We report the clinical course of a diabetic patient with bilateral cataract and rubeosis in association with ocular ischemic syndrome and initially treated him with simultaneous intravitreal 2 mg aflibercept and 2 mg triamcinolone acetonide injection at the same setting prior to planned cataract sur...
Saved in:
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2017-01-01
|
| Series: | Case Reports in Ophthalmological Medicine |
| Online Access: | http://dx.doi.org/10.1155/2017/5123963 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832564244836515840 |
|---|---|
| author | Ceren Durmaz Engin Ziya Ayhan Süleyman Men Aylin Yaman A. Osman Saatci |
| author_facet | Ceren Durmaz Engin Ziya Ayhan Süleyman Men Aylin Yaman A. Osman Saatci |
| author_sort | Ceren Durmaz Engin |
| collection | DOAJ |
| description | We report the clinical course of a diabetic patient with bilateral cataract and rubeosis in association with ocular ischemic syndrome and initially treated him with simultaneous intravitreal 2 mg aflibercept and 2 mg triamcinolone acetonide injection at the same setting prior to planned cataract surgery and further photocoagulation. However, sterile anterior segment inflammation characterized by hypopyon occurred four days apart in OU. Right eye developed the sterile inflammation at the third postinjection day and the left eye developed the sterile inflammation at the seventh postinjection day (two days after the uneventful cataract surgery with intraocular lens implantation) without any pain or significant redness. Vitreous biopsy taken during the right phacovitrectomy was negative for any microbial contamination. Both eyes were treated successfully with intensive topical prednisolone acetate with a relatively good visual outcome. It is likely that underlying ocular ischemic syndrome might have facilitated the formation of sterile inflammation as blood-aqueous barrier disruption and flare have already been present. |
| format | Article |
| id | doaj-art-17ccb76b5e914010aa3341ccefc91949 |
| institution | Kabale University |
| issn | 2090-6722 2090-6730 |
| language | English |
| publishDate | 2017-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Ophthalmological Medicine |
| spelling | doaj-art-17ccb76b5e914010aa3341ccefc919492025-02-03T01:11:27ZengWileyCase Reports in Ophthalmological Medicine2090-67222090-67302017-01-01201710.1155/2017/51239635123963Bilateral Severe Sterile Inflammation with Hypopyon after Simultaneous Intravitreal Triamcinolone Acetonide and Aflibercept Injection in a Patient with Bilateral Marked Rubeosis Associated with Ocular Ischemic SyndromeCeren Durmaz Engin0Ziya Ayhan1Süleyman Men2Aylin Yaman3A. Osman Saatci4Department of Ophthalmology, Dokuz Eylul University, Izmir, TurkeyDepartment of Ophthalmology, Dokuz Eylul University, Izmir, TurkeyDepartment of Radiology, Dokuz Eylul University, Izmir, TurkeyDepartment of Ophthalmology, Dokuz Eylul University, Izmir, TurkeyDepartment of Ophthalmology, Dokuz Eylul University, Izmir, TurkeyWe report the clinical course of a diabetic patient with bilateral cataract and rubeosis in association with ocular ischemic syndrome and initially treated him with simultaneous intravitreal 2 mg aflibercept and 2 mg triamcinolone acetonide injection at the same setting prior to planned cataract surgery and further photocoagulation. However, sterile anterior segment inflammation characterized by hypopyon occurred four days apart in OU. Right eye developed the sterile inflammation at the third postinjection day and the left eye developed the sterile inflammation at the seventh postinjection day (two days after the uneventful cataract surgery with intraocular lens implantation) without any pain or significant redness. Vitreous biopsy taken during the right phacovitrectomy was negative for any microbial contamination. Both eyes were treated successfully with intensive topical prednisolone acetate with a relatively good visual outcome. It is likely that underlying ocular ischemic syndrome might have facilitated the formation of sterile inflammation as blood-aqueous barrier disruption and flare have already been present.http://dx.doi.org/10.1155/2017/5123963 |
| spellingShingle | Ceren Durmaz Engin Ziya Ayhan Süleyman Men Aylin Yaman A. Osman Saatci Bilateral Severe Sterile Inflammation with Hypopyon after Simultaneous Intravitreal Triamcinolone Acetonide and Aflibercept Injection in a Patient with Bilateral Marked Rubeosis Associated with Ocular Ischemic Syndrome Case Reports in Ophthalmological Medicine |
| title | Bilateral Severe Sterile Inflammation with Hypopyon after Simultaneous Intravitreal Triamcinolone Acetonide and Aflibercept Injection in a Patient with Bilateral Marked Rubeosis Associated with Ocular Ischemic Syndrome |
| title_full | Bilateral Severe Sterile Inflammation with Hypopyon after Simultaneous Intravitreal Triamcinolone Acetonide and Aflibercept Injection in a Patient with Bilateral Marked Rubeosis Associated with Ocular Ischemic Syndrome |
| title_fullStr | Bilateral Severe Sterile Inflammation with Hypopyon after Simultaneous Intravitreal Triamcinolone Acetonide and Aflibercept Injection in a Patient with Bilateral Marked Rubeosis Associated with Ocular Ischemic Syndrome |
| title_full_unstemmed | Bilateral Severe Sterile Inflammation with Hypopyon after Simultaneous Intravitreal Triamcinolone Acetonide and Aflibercept Injection in a Patient with Bilateral Marked Rubeosis Associated with Ocular Ischemic Syndrome |
| title_short | Bilateral Severe Sterile Inflammation with Hypopyon after Simultaneous Intravitreal Triamcinolone Acetonide and Aflibercept Injection in a Patient with Bilateral Marked Rubeosis Associated with Ocular Ischemic Syndrome |
| title_sort | bilateral severe sterile inflammation with hypopyon after simultaneous intravitreal triamcinolone acetonide and aflibercept injection in a patient with bilateral marked rubeosis associated with ocular ischemic syndrome |
| url | http://dx.doi.org/10.1155/2017/5123963 |
| work_keys_str_mv | AT cerendurmazengin bilateralseveresterileinflammationwithhypopyonaftersimultaneousintravitrealtriamcinoloneacetonideandafliberceptinjectioninapatientwithbilateralmarkedrubeosisassociatedwithocularischemicsyndrome AT ziyaayhan bilateralseveresterileinflammationwithhypopyonaftersimultaneousintravitrealtriamcinoloneacetonideandafliberceptinjectioninapatientwithbilateralmarkedrubeosisassociatedwithocularischemicsyndrome AT suleymanmen bilateralseveresterileinflammationwithhypopyonaftersimultaneousintravitrealtriamcinoloneacetonideandafliberceptinjectioninapatientwithbilateralmarkedrubeosisassociatedwithocularischemicsyndrome AT aylinyaman bilateralseveresterileinflammationwithhypopyonaftersimultaneousintravitrealtriamcinoloneacetonideandafliberceptinjectioninapatientwithbilateralmarkedrubeosisassociatedwithocularischemicsyndrome AT aosmansaatci bilateralseveresterileinflammationwithhypopyonaftersimultaneousintravitrealtriamcinoloneacetonideandafliberceptinjectioninapatientwithbilateralmarkedrubeosisassociatedwithocularischemicsyndrome |