Resting-state functional magnetic resonance imaging study on cerebrovascular reactivity changes in the precuneus of Alzheimer’s disease and mild cognitive impairment patients

Resting-state functional magnetic resonance imaging study on cerebrovascular reactivity changes in the precuneus of Alzheimer’s disease and mild cognitive impairment patients

Abstract Alzheimer’s disease (AD) is a progressive neurodegenerative disorder characterized by memory impairment and cognitive decline, ultimately culminating in dementia. This study aims to evaluate cerebrovascular reactivity (CVR) and functional connectivity (FC) in patients with AD and mild cogni...

Full description

Saved in:

Bibliographic Details
Main Authors:	Xue Tang, Luoyu Wang, Qi Feng, Hanjun Hu, Yidi Zhu, Zhengluan Liao, Zhongxiang Ding, Xiufang Xu
Format:	Article
Language:	English
Published:	Nature Portfolio 2025-01-01
Series:	Scientific Reports
Subjects:	Alzheimer’s disease mild cognitive impairment resting-state functional magnetic resonance imaging cerebrovascular reactivity
Online Access:	https://doi.org/10.1038/s41598-024-82769-x
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

Unraveling the influences of hemodynamic lag and intrinsic cerebrovascular reactivity on functional metrics in ischemic stroke
by: Luoyu Wang, et al.
Published: (2024-12-01)

Structural connectivity of the precuneus and its relation to resting-state networks
by: Atsushi Yamaguchi, et al.
Published: (2024-12-01)

Resting-State Brain Network Characteristics Related to Mild Cognitive Impairment: A Preliminary fNIRS Proof-of-Concept Study
by: Guohui Yang, et al.
Published: (2025-01-01)

The Greek Version of the Mild Behavioral Impairment Checklist (MBI-C): Psychometric Properties in Mild Cognitive Impairment Due to Alzheimer’s Disease
by: Efthalia Angelopoulou, et al.
Published: (2025-04-01)

A multi-modal study on cerebrovascular dysfunction in cognitive decline of de novo Parkinson’s disease
by: Hongwei Li, et al.
Published: (2025-01-01)

Review of the prevalence of Mild Behavioral Impairment subdomains in populations from cognitively normal to Mild Cognitive Impairment according to International Society for Advanced Alzheimer's Research and Treatment criteria
by: Virginia Quicchi
Published: (2023-08-01)

Efficacy of Cellex in patients with mild cognitive impairment
by: B. A. Abusueva, et al.
Published: (2019-04-01)

Impaired Cerebral Hemodynamics in Asymptomatic Carotid Artery Stenosis Assessed by Resting-State Functional MRI
by: Kaio F. Secchinato, et al.
Published: (2025-04-01)

Dynamic changes and prognostic value of glutathione S-transferase alpha in mild cognitive impairment and Alzheimer’s disease
by: Yangyang Tang, et al.
Published: (2024-12-01)

Older Adults With Smaller and Less Complex Social Networks Show Deficits in Medial Temporal Cerebrovascular Reactivity
by: Evelyn Chang, et al.
Published: (2024-08-01)

Repetitive transcranial magnetic stimulation may promote the reversion of mild cognitive impairment to normal cognition
by: Zhiwei Guo, et al.
Published: (2025-04-01)

Hearing loss is associated with decreased default-mode network connectivity in individuals with mild cognitive impairment
by: Nicole Grant, et al.
Published: (2023-12-01)

Associations Between Intracranial Pressure Extremes and Continuous Metrics of Cerebrovascular Pressure Reactivity in Acute Traumatic Neural Injury: A Scoping Review
by: Kevin Y. Stein, et al.
Published: (2024-11-01)

The restoration of REST inhibits reactivity of Down syndrome iPSC-derived astrocytes
by: Tan Huang, et al.
Published: (2025-03-01)

Aβ‐reactive T cell polyfunctionality response as a new biomarker for mild cognitive impairment
by: Yen‐Ling Chiu, et al.
Published: (2025-01-01)

An exploration of distinguishing subjective cognitive decline and mild cognitive impairment based on resting-state prefrontal functional connectivity assessed by functional near-infrared spectroscopy
by: Zhengping Pu, et al.
Published: (2025-01-01)

Changes in cerebrovascular reactivity within functional networks in older adults with long-COVID
by: Jessica M. Pommy, et al.
Published: (2025-03-01)

Cognitive Effect of Levetiracetam in Patients with Alzheimer’s Disease or Mild Cognitive Impairment: A Systematic Review
by: Mohamad Hosein Mohamadi, MD, et al.
Published: (2025-01-01)

Multiparameter resting-state functional magnetic resonance imaging as an indicator of neuropsychological changes in Binswanger’s disease with mild cognitive impairment
by: Haiyi Zhang, et al.
Published: (2025-02-01)

New possibilities for the treatment of mild cognitive impairment and prevention of dementia in patients with cerebrovascular disease. Results of the PRIORITET Observation Program
by: E. Y. Solovieva, et al.
Published: (2023-02-01)

Quality of Life in Mild Cognitive Impairment and Mild Dementia Associated with Alzheimer’s Disease: A Systematic Review
by: Joanna Campbell, et al.
Published: (2024-11-01)

Detection of Alzheimer and mild cognitive impairment patients by Poincare and Entropy methods based on electroencephalography signals
by: Umut Aslan, et al.
Published: (2025-04-01)

Distinguishing Early from Late Mild Cognitive Impairment Using Magnetic Resonance Free-Water Diffusion Tensor Imaging
by: Maurizio Bergamino, et al.
Published: (2025-01-01)

A longitudinal study of functional brain complexity in progressive Alzheimer's disease
by: Ru Zhang, et al.
Published: (2025-01-01)

Cerebrovascular reactivity depending on rheumatoid factor and anticitrullinated protein antibody positivity in hypertensive patients with rheumatoid arthritis
by: N. V. Rebrova, et al.
Published: (2022-07-01)

Effects of resistance exercise intensity on cerebral blood flow and cerebrovascular reactivity in healthy young males: A pilot study
by: Zusheng Li, et al.
Published: (2025-05-01)

Mild Neurocognitive Disorder: Clinical Manifestations and Treatment
by: Jesús Serrano Ruíz
Published: (2025-01-01)

A systematic review and meta-analysis of pteridines in mild cognitive impairment and Alzheimer’s disease
by: Arduino A. Mangoni, et al.
Published: (2025-02-01)

Assessing and Improving the Reproducibility of Cerebrovascular Reactivity Evaluations in Healthy Subjects Using Short-Breath-Hold fMRI
by: Emely Renger, et al.
Published: (2025-08-01)

Input Shaping Control of a Flexible Structure for Rest-to-Rest and Non-Rest-to-Rest Maneuvers
by: Shambo Bhattacharjee, et al.
Published: (2025-03-01)

Adherence to treatment in patients with cerebrovascular disease as a multifactorial problem
by: M. M. Tanashyan, et al.
Published: (2023-02-01)

The role of cerebrovascular reactivity on brain activation during a working memory task in type 2 diabetes
by: Yarden Oliel, et al.
Published: (2025-01-01)

Effect of aspirin use on conversion risk from mild cognitive impairment to Alzheimer’s disease
by: Bo Kyu Choi, et al.
Published: (2025-08-01)

The role of quantitative EEG biomarkers in Alzheimer’s disease and mild cognitive impairment: applications and insights
by: Yue Yuan, et al.
Published: (2025-04-01)

Intervention Effects of the Holistic Physio-Cognitive Rehabilitation for Alzheimer Disease and Mild Cognitive Impairment
by: Aiko Osawa, et al.
Published: (2025-06-01)

Breath holding for 20 s following extended expiration is a practical, effective and robust standard when measuring cerebrovascular reactivity in healthy adults using BOLD fMRI at 3 T
by: Jörg Larsen, et al.
Published: (2021-06-01)

Superiority illusion in older adults: Volume and functional connectivity of the precuneus
by: Yuki Shidei, et al.
Published: (2025-03-01)

Sarcopenia index is associated with Alzheimer’s disease, mild cognitive impairment and their mortality in Chinese adults aged 65 and older
by: Chenxi Ren, et al.
Published: (2025-07-01)

Hypothalamic atrophy and structural covariance in amnestic mild cognitive impairment and Alzheimer’s dementia
by: Hannah Pecher, et al.
Published: (2024-01-01)

Correlating retinal and choroidal vascular parameters with volumetric MRI in Alzheimer’s disease and amnestic mild cognitive impairment
by: Wufan Zhao, et al.
Published: (2025-07-01)