Case Report: Two cases of IgG4-related kidney disease with monoclonal gammopathy

Case Report: Two cases of IgG4-related kidney disease with monoclonal gammopathy

IntroductionIgG4-related disease (IgG4-RD) is a newly classified but poorly understood immune-medicated systemic disease. Monoclonal gammopathy encompasses a spectrum of disorders driven by clonal plasma cell proliferation, leading to the presence of monoclonal immunoglobulins (M-proteins) in serum...

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Bibliographic Details
Main Authors:	Qian Dong, Xuanli Tang, Jiang Liu, Pengjie Xu
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-06-01
Series:	Frontiers in Immunology
Subjects:	IgG4-related kidney disease IgG4-related tubulointerstitial nephritis (IgG4-TIN) secondary membranous nephropathy (SMN) monoclonal gammopathy of renal significance (MGRS) monoclonal gammopathy of undetermined significance (MGUS)
Online Access:	https://www.frontiersin.org/articles/10.3389/fimmu.2025.1539441/full
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