The effect of recombinant interferon alpha-2b on the relative content of CD56<sup>bright</sup> NK cells in the peripheral blood of pregnant women with chronic urogenital infections
Physiological immunodeficiency during pregnancy contributes to activation of chronic urogenital pathology which often causes intrauterine infections. Recombinant interferon-alpha based rectal suppositories VIFERON® are often used in Russia for treatment of pregnant women with urogenital pathology. T...
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| Format: | Article |
| Language: | Russian |
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Ministry of Health of the Russian Federation. Federal State Budgetary Institution «Scientific Centre for Expert Evaluation of Medicinal Products»
2018-02-01
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| Series: | Биопрепараты: Профилактика, диагностика, лечение |
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| Online Access: | https://www.biopreparations.ru/jour/article/view/82 |
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| _version_ | 1849342819200663552 |
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| author | E. N. Vyzhlova V. V. Malinovskaya E. V. Dmitrieva S. V. Novikova |
| author_facet | E. N. Vyzhlova V. V. Malinovskaya E. V. Dmitrieva S. V. Novikova |
| author_sort | E. N. Vyzhlova |
| collection | DOAJ |
| description | Physiological immunodeficiency during pregnancy contributes to activation of chronic urogenital pathology which often causes intrauterine infections. Recombinant interferon-alpha based rectal suppositories VIFERON® are often used in Russia for treatment of pregnant women with urogenital pathology. The treatment results in a marked decrease in the number of pregnancy complications and perinatal pathology accompanied by a decrease in peripheral blood CD56bright natural killer cells. |
| format | Article |
| id | doaj-art-17a9cdb861ca46d3ac43a0417cf5ce80 |
| institution | Kabale University |
| issn | 2221-996X 2619-1156 |
| language | Russian |
| publishDate | 2018-02-01 |
| publisher | Ministry of Health of the Russian Federation. Federal State Budgetary Institution «Scientific Centre for Expert Evaluation of Medicinal Products» |
| record_format | Article |
| series | Биопрепараты: Профилактика, диагностика, лечение |
| spelling | doaj-art-17a9cdb861ca46d3ac43a0417cf5ce802025-08-20T03:43:15ZrusMinistry of Health of the Russian Federation. Federal State Budgetary Institution «Scientific Centre for Expert Evaluation of Medicinal Products»Биопрепараты: Профилактика, диагностика, лечение2221-996X2619-11562018-02-01171545882The effect of recombinant interferon alpha-2b on the relative content of CD56<sup>bright</sup> NK cells in the peripheral blood of pregnant women with chronic urogenital infectionsE. N. Vyzhlova0V. V. Malinovskaya1E. V. Dmitrieva2S. V. Novikova3Federal Research Centre for Epidemiology and Microbiology named after the honorary academician N. F. GamaleyaFederal Research Centre for Epidemiology and Microbiology named after the honorary academician N. F. GamaleyaFederal Research Centre for Epidemiology and Microbiology named after the honorary academician N. F. GamaleyaScientific Research Institute of Obstetrics and Gynecology of the Moscow RegionPhysiological immunodeficiency during pregnancy contributes to activation of chronic urogenital pathology which often causes intrauterine infections. Recombinant interferon-alpha based rectal suppositories VIFERON® are often used in Russia for treatment of pregnant women with urogenital pathology. The treatment results in a marked decrease in the number of pregnancy complications and perinatal pathology accompanied by a decrease in peripheral blood CD56bright natural killer cells.https://www.biopreparations.ru/jour/article/view/82беременностьурогенитальные инфекциивнутриутробные инфекциирекомбинантный интерферон альфа-2bcd56<sup>bright</sup>-популяция натуральных киллеровpregnancyurogenital pathologyintrauterine infectionsrecombinant interferon-alphacd56<sup>bright</sup> natural killer cells |
| spellingShingle | E. N. Vyzhlova V. V. Malinovskaya E. V. Dmitrieva S. V. Novikova The effect of recombinant interferon alpha-2b on the relative content of CD56<sup>bright</sup> NK cells in the peripheral blood of pregnant women with chronic urogenital infections Биопрепараты: Профилактика, диагностика, лечение беременность урогенитальные инфекции внутриутробные инфекции рекомбинантный интерферон альфа-2b cd56<sup>bright</sup>-популяция натуральных киллеров pregnancy urogenital pathology intrauterine infections recombinant interferon-alpha cd56<sup>bright</sup> natural killer cells |
| title | The effect of recombinant interferon alpha-2b on the relative content of CD56<sup>bright</sup> NK cells in the peripheral blood of pregnant women with chronic urogenital infections |
| title_full | The effect of recombinant interferon alpha-2b on the relative content of CD56<sup>bright</sup> NK cells in the peripheral blood of pregnant women with chronic urogenital infections |
| title_fullStr | The effect of recombinant interferon alpha-2b on the relative content of CD56<sup>bright</sup> NK cells in the peripheral blood of pregnant women with chronic urogenital infections |
| title_full_unstemmed | The effect of recombinant interferon alpha-2b on the relative content of CD56<sup>bright</sup> NK cells in the peripheral blood of pregnant women with chronic urogenital infections |
| title_short | The effect of recombinant interferon alpha-2b on the relative content of CD56<sup>bright</sup> NK cells in the peripheral blood of pregnant women with chronic urogenital infections |
| title_sort | effect of recombinant interferon alpha 2b on the relative content of cd56 sup bright sup nk cells in the peripheral blood of pregnant women with chronic urogenital infections |
| topic | беременность урогенитальные инфекции внутриутробные инфекции рекомбинантный интерферон альфа-2b cd56<sup>bright</sup>-популяция натуральных киллеров pregnancy urogenital pathology intrauterine infections recombinant interferon-alpha cd56<sup>bright</sup> natural killer cells |
| url | https://www.biopreparations.ru/jour/article/view/82 |
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