Biocontrol Activity of <i>Alternaria angustiovoidea</i> Against <i>Trichothecium roseum</i> Through Inhibiting Its Growth, Pathogenicity, and Gene Expression

Apple mold heart disease, primarily caused by <i>Trichothecium roseum</i>, is the most severe disease affecting stored apples. Developing biocontrol resources as an alternative to chemical pesticides is crucial for the advancement of green agriculture. This study demonstrated that a path...

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Main Authors: Xiuna Guo, Meiting Xu, Shaoli Wang, Wei Zhang, Baoyou Liu
Format: Article
Language:English
Published: MDPI AG 2025-02-01
Series:Agronomy
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Online Access:https://www.mdpi.com/2073-4395/15/3/547
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author Xiuna Guo
Meiting Xu
Shaoli Wang
Wei Zhang
Baoyou Liu
author_facet Xiuna Guo
Meiting Xu
Shaoli Wang
Wei Zhang
Baoyou Liu
author_sort Xiuna Guo
collection DOAJ
description Apple mold heart disease, primarily caused by <i>Trichothecium roseum</i>, is the most severe disease affecting stored apples. Developing biocontrol resources as an alternative to chemical pesticides is crucial for the advancement of green agriculture. This study demonstrated that a pathogenic fungus isolated from sunflower leaves exhibited specific inhibitory effects against <i>T. roseum</i>. Through morphological observation, identification, and the construction of a phylogenetic tree analysis, the fungus was identified as <i>Alternaria angustiovoidea</i>. GW2A was found to inhibit the spread of diseases on apple twigs. Additionally, GW2A has significant preventive and therapeutic effects on apple mold heart disease. Furthermore, GW2A can induce apple trees to upregulate defense-related genes, thereby enhancing resistance. Transcriptome analysis revealed that GW2A inhibits <i>T. roseum</i> growth by suppressing the function of polysaccharide hydrolases, oxidoreductases, and intermediate steps in carbohydrate metabolism. In conclusion, our research has effectively isolated and characterized <i>A. angustiovoidea</i>, revealing its significant potential as a biocontrol agent against <i>T. roseum</i> and apple mold heart disease, particularly in areas where sunflowers and apple trees are not co-cultivated. Additionally, we demonstrated its ability to induce resistance in apple trees, offering a sustainable approach to disease management in apple cultivation.
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institution Kabale University
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publisher MDPI AG
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series Agronomy
spelling doaj-art-17a90e5db6d44682bd6beded1258b71d2025-08-20T03:40:42ZengMDPI AGAgronomy2073-43952025-02-0115354710.3390/agronomy15030547Biocontrol Activity of <i>Alternaria angustiovoidea</i> Against <i>Trichothecium roseum</i> Through Inhibiting Its Growth, Pathogenicity, and Gene ExpressionXiuna Guo0Meiting Xu1Shaoli Wang2Wei Zhang3Baoyou Liu4College of Horticulture, Ludong University, No. 186 Hongqizhong Road, Yantai 264025, ChinaCollege of Horticulture, Ludong University, No. 186 Hongqizhong Road, Yantai 264025, ChinaYantai Academy of Agricultural Sciences, No. 26 West Gangcheng Avenue, Yantai 265559, ChinaYantai Academy of Agricultural Sciences, No. 26 West Gangcheng Avenue, Yantai 265559, ChinaYantai Academy of Agricultural Sciences, No. 26 West Gangcheng Avenue, Yantai 265559, ChinaApple mold heart disease, primarily caused by <i>Trichothecium roseum</i>, is the most severe disease affecting stored apples. Developing biocontrol resources as an alternative to chemical pesticides is crucial for the advancement of green agriculture. This study demonstrated that a pathogenic fungus isolated from sunflower leaves exhibited specific inhibitory effects against <i>T. roseum</i>. Through morphological observation, identification, and the construction of a phylogenetic tree analysis, the fungus was identified as <i>Alternaria angustiovoidea</i>. GW2A was found to inhibit the spread of diseases on apple twigs. Additionally, GW2A has significant preventive and therapeutic effects on apple mold heart disease. Furthermore, GW2A can induce apple trees to upregulate defense-related genes, thereby enhancing resistance. Transcriptome analysis revealed that GW2A inhibits <i>T. roseum</i> growth by suppressing the function of polysaccharide hydrolases, oxidoreductases, and intermediate steps in carbohydrate metabolism. In conclusion, our research has effectively isolated and characterized <i>A. angustiovoidea</i>, revealing its significant potential as a biocontrol agent against <i>T. roseum</i> and apple mold heart disease, particularly in areas where sunflowers and apple trees are not co-cultivated. Additionally, we demonstrated its ability to induce resistance in apple trees, offering a sustainable approach to disease management in apple cultivation.https://www.mdpi.com/2073-4395/15/3/547<i>Alternaria angustiovoidea</i>biocontrol resources<i>Trichothecium roseum</i>apple mold heart diseaseinduced resistance
spellingShingle Xiuna Guo
Meiting Xu
Shaoli Wang
Wei Zhang
Baoyou Liu
Biocontrol Activity of <i>Alternaria angustiovoidea</i> Against <i>Trichothecium roseum</i> Through Inhibiting Its Growth, Pathogenicity, and Gene Expression
Agronomy
<i>Alternaria angustiovoidea</i>
biocontrol resources
<i>Trichothecium roseum</i>
apple mold heart disease
induced resistance
title Biocontrol Activity of <i>Alternaria angustiovoidea</i> Against <i>Trichothecium roseum</i> Through Inhibiting Its Growth, Pathogenicity, and Gene Expression
title_full Biocontrol Activity of <i>Alternaria angustiovoidea</i> Against <i>Trichothecium roseum</i> Through Inhibiting Its Growth, Pathogenicity, and Gene Expression
title_fullStr Biocontrol Activity of <i>Alternaria angustiovoidea</i> Against <i>Trichothecium roseum</i> Through Inhibiting Its Growth, Pathogenicity, and Gene Expression
title_full_unstemmed Biocontrol Activity of <i>Alternaria angustiovoidea</i> Against <i>Trichothecium roseum</i> Through Inhibiting Its Growth, Pathogenicity, and Gene Expression
title_short Biocontrol Activity of <i>Alternaria angustiovoidea</i> Against <i>Trichothecium roseum</i> Through Inhibiting Its Growth, Pathogenicity, and Gene Expression
title_sort biocontrol activity of i alternaria angustiovoidea i against i trichothecium roseum i through inhibiting its growth pathogenicity and gene expression
topic <i>Alternaria angustiovoidea</i>
biocontrol resources
<i>Trichothecium roseum</i>
apple mold heart disease
induced resistance
url https://www.mdpi.com/2073-4395/15/3/547
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