The effect of oral curcumin on vincristine-induced neuropathy in pediatric acute lymphoblastic leukemia: A double-blind randomized controlled clinical trial

The effect of oral curcumin on vincristine-induced neuropathy in pediatric acute lymphoblastic leukemia: A double-blind randomized controlled clinical trial

Abstract Background Peripheral neuropathy is a major adverse effect of Vincristine (VCR) in pediatric acute lymphoblastic leukemia (ALL) patients. Curcumin can prevent the development of many neurological diseases. Method This clinical trial study was conducted on 141 pediatric ALL patients, all ove...

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Bibliographic Details
Main Authors: Aziz Eghbali, Mahsa Adibifar, Ali Ghasemi, Roghayeh Rahimi Afzal, Katayoun Moradi, Aygin Eghbali, Foroozan Faress, Kazem Ghaffari
Format: Article
Language:English
Published: BMC 2025-02-01
Series:BMC Cancer
Subjects:
Curcumin
Acute lymphoblastic leukemia
Pediatrics
Vincristine
Neuropathy
Online Access:https://doi.org/10.1186/s12885-025-13751-7
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