Botulinum toxin in modern clinical and aesthetic medicine: history, applications, risks and future perspectives
Botulinum toxin, a potent neurotoxin produced by Clostridium botulinum, has widespread applications in both medical and aesthetic practices due to its ability to inhibit neuromuscular transmission. In clinical medicine, it is used to treat various conditions such as chronic migraines, spasticity, an...
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| Format: | Article |
| Language: | English |
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Pensoft Publishers
2025-06-01
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| Series: | Pharmacia |
| Online Access: | https://pharmacia.pensoft.net/article/149331/download/pdf/ |
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| author | Gabriela Kehayova Stela Dragomanova Simeonka Dimitrova |
| author_facet | Gabriela Kehayova Stela Dragomanova Simeonka Dimitrova |
| author_sort | Gabriela Kehayova |
| collection | DOAJ |
| description | Botulinum toxin, a potent neurotoxin produced by Clostridium botulinum, has widespread applications in both medical and aesthetic practices due to its ability to inhibit neuromuscular transmission. In clinical medicine, it is used to treat various conditions such as chronic migraines, spasticity, and hyperhidrosis. In aesthetic medicine, it is primarily employed for wrinkle reduction and facial rejuvenation, providing significant efficacy with minimal recovery time. Despite its established therapeutic benefits, improper administration of botulinum toxin can lead to serious adverse effects, including muscle weakness, respiratory compromise, and localised reactions. Therefore, it is essential to ensure precise dosing, skilled injection techniques, and appropriate patient selection to maximise therapeutic outcomes while minimising risks. As the use of botulinum toxin continues to expand in both medical and cosmetic settings, there is a critical need for enhanced safety protocols and stringent regulation to ensure its safe and effective application. |
| format | Article |
| id | doaj-art-17a6aeada91a40558d089c83cbb0e5dd |
| institution | OA Journals |
| issn | 2603-557X |
| language | English |
| publishDate | 2025-06-01 |
| publisher | Pensoft Publishers |
| record_format | Article |
| series | Pharmacia |
| spelling | doaj-art-17a6aeada91a40558d089c83cbb0e5dd2025-08-20T02:36:27ZengPensoft PublishersPharmacia2603-557X2025-06-017211010.3897/pharmacia.72.e149331149331Botulinum toxin in modern clinical and aesthetic medicine: history, applications, risks and future perspectivesGabriela Kehayova0Stela Dragomanova1Simeonka Dimitrova2Medical University “Prof. Paraskev Stoyanov”Medical University “Prof. Paraskev Stoyanov”Medical University “Prof. Paraskev Stoyanov”Botulinum toxin, a potent neurotoxin produced by Clostridium botulinum, has widespread applications in both medical and aesthetic practices due to its ability to inhibit neuromuscular transmission. In clinical medicine, it is used to treat various conditions such as chronic migraines, spasticity, and hyperhidrosis. In aesthetic medicine, it is primarily employed for wrinkle reduction and facial rejuvenation, providing significant efficacy with minimal recovery time. Despite its established therapeutic benefits, improper administration of botulinum toxin can lead to serious adverse effects, including muscle weakness, respiratory compromise, and localised reactions. Therefore, it is essential to ensure precise dosing, skilled injection techniques, and appropriate patient selection to maximise therapeutic outcomes while minimising risks. As the use of botulinum toxin continues to expand in both medical and cosmetic settings, there is a critical need for enhanced safety protocols and stringent regulation to ensure its safe and effective application.https://pharmacia.pensoft.net/article/149331/download/pdf/ |
| spellingShingle | Gabriela Kehayova Stela Dragomanova Simeonka Dimitrova Botulinum toxin in modern clinical and aesthetic medicine: history, applications, risks and future perspectives Pharmacia |
| title | Botulinum toxin in modern clinical and aesthetic medicine: history, applications, risks and future perspectives |
| title_full | Botulinum toxin in modern clinical and aesthetic medicine: history, applications, risks and future perspectives |
| title_fullStr | Botulinum toxin in modern clinical and aesthetic medicine: history, applications, risks and future perspectives |
| title_full_unstemmed | Botulinum toxin in modern clinical and aesthetic medicine: history, applications, risks and future perspectives |
| title_short | Botulinum toxin in modern clinical and aesthetic medicine: history, applications, risks and future perspectives |
| title_sort | botulinum toxin in modern clinical and aesthetic medicine history applications risks and future perspectives |
| url | https://pharmacia.pensoft.net/article/149331/download/pdf/ |
| work_keys_str_mv | AT gabrielakehayova botulinumtoxininmodernclinicalandaestheticmedicinehistoryapplicationsrisksandfutureperspectives AT steladragomanova botulinumtoxininmodernclinicalandaestheticmedicinehistoryapplicationsrisksandfutureperspectives AT simeonkadimitrova botulinumtoxininmodernclinicalandaestheticmedicinehistoryapplicationsrisksandfutureperspectives |