Push–pull fluorophores based on NHS esters of bithiophene for labelling of biomolecules containing primary amines

Push–pull fluorophores based on NHS esters of bithiophene for labelling of biomolecules containing primary amines

Fluorescent labelling is a versatile tool to visualize biomolecules containing primary amines in their cellular environment, allowing the study of their function or interactions. Here, three organic fluorophores that can irreversibly bind to the primary amine group on the target biomolecule are repo...

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Bibliographic Details
Main Authors: Mariana Barros, Pau Arroyo, Jose A. Sáez, Salvador Gil, Margarita Parra, Susana P. G. Costa, M. Manuela M. Raposo, Pablo Gaviña
Format: Article
Language:English
Published: The Royal Society 2025-02-01
Series:Royal Society Open Science
Subjects:
fluorescent labelling
push–pull heterocyclic fluorophores
bithiophene
Boc-lysine
primary amine chemosensor
Online Access:https://royalsocietypublishing.org/doi/10.1098/rsos.241816
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