SURGERY FOR DRUG-RESISTANT DESTRUCTIVE PULMONARY TUBERCULOSIS

The paper presents the experience in surgically treating 145 patients with destructive, mainly fibrocavernous pulmonary tuberculosis. All the patients completed treatment. In the preoperative preparation, particular emphasis is laid on the promptest determination of a spectrum of pathogen susceptibi...

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Main Authors: S. N. Skornyakov, I. Ya. Motus, E. I. Kildyusheva, I. D. Medvinsky, A. V. Bazhenov, A. V. Savelyev
Format: Article
Language:Russian
Published: New Terra Publishing House 2015-03-01
Series:Туберкулез и болезни лёгких
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Online Access:https://www.tibl-journal.com/jour/article/view/346
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author S. N. Skornyakov
I. Ya. Motus
E. I. Kildyusheva
I. D. Medvinsky
A. V. Bazhenov
A. V. Savelyev
author_facet S. N. Skornyakov
I. Ya. Motus
E. I. Kildyusheva
I. D. Medvinsky
A. V. Bazhenov
A. V. Savelyev
author_sort S. N. Skornyakov
collection DOAJ
description The paper presents the experience in surgically treating 145 patients with destructive, mainly fibrocavernous pulmonary tuberculosis. All the patients completed treatment. In the preoperative preparation, particular emphasis is laid on the promptest determination of a spectrum of pathogen susceptibility/resistance, individualized chemotherapy, and collapse therapy options. Postoperative complications occurred in 27 (18.6%) patients, fatal outcomes in 4 (2.7%). The former were recorded most frequently after pneumonectomy in 13 (37.1%) cases, the later were seen in 3 (8.6%). Sputum culture conversion was generally achieved in 111 (78%) patients, particularly in 97 (78.2%) patients with multidrug-resistant tuberculosis and in 14 (66.7%) with a broad drug resistance in the pathogen. Out of the 64 patients followed up for more than 3 years, 48 (75.0%) were in clinical and bacteriological remission.
format Article
id doaj-art-179967b8dadc43b483e639ae9546bbd2
institution DOAJ
issn 2075-1230
2542-1506
language Russian
publishDate 2015-03-01
publisher New Terra Publishing House
record_format Article
series Туберкулез и болезни лёгких
spelling doaj-art-179967b8dadc43b483e639ae9546bbd22025-08-20T03:02:32ZrusNew Terra Publishing HouseТуберкулез и болезни лёгких2075-12302542-15062015-03-01031521346SURGERY FOR DRUG-RESISTANT DESTRUCTIVE PULMONARY TUBERCULOSISS. N. Skornyakov0I. Ya. Motus1E. I. Kildyusheva2I. D. Medvinsky3A. V. Bazhenov4A. V. Savelyev5Ural Reseach Institute of PhthisiologyUral Reseach Institute of PhthisiologyUral Reseach Institute of PhthisiologyUral Reseach Institute of PhthisiologyUral Reseach Institute of PhthisiologyUral Reseach Institute of PhthisiologyThe paper presents the experience in surgically treating 145 patients with destructive, mainly fibrocavernous pulmonary tuberculosis. All the patients completed treatment. In the preoperative preparation, particular emphasis is laid on the promptest determination of a spectrum of pathogen susceptibility/resistance, individualized chemotherapy, and collapse therapy options. Postoperative complications occurred in 27 (18.6%) patients, fatal outcomes in 4 (2.7%). The former were recorded most frequently after pneumonectomy in 13 (37.1%) cases, the later were seen in 3 (8.6%). Sputum culture conversion was generally achieved in 111 (78%) patients, particularly in 97 (78.2%) patients with multidrug-resistant tuberculosis and in 14 (66.7%) with a broad drug resistance in the pathogen. Out of the 64 patients followed up for more than 3 years, 48 (75.0%) were in clinical and bacteriological remission.https://www.tibl-journal.com/jour/article/view/346drug resistance in pathogenpulmonary tuberculosis
spellingShingle S. N. Skornyakov
I. Ya. Motus
E. I. Kildyusheva
I. D. Medvinsky
A. V. Bazhenov
A. V. Savelyev
SURGERY FOR DRUG-RESISTANT DESTRUCTIVE PULMONARY TUBERCULOSIS
Туберкулез и болезни лёгких
drug resistance in pathogen
pulmonary tuberculosis
title SURGERY FOR DRUG-RESISTANT DESTRUCTIVE PULMONARY TUBERCULOSIS
title_full SURGERY FOR DRUG-RESISTANT DESTRUCTIVE PULMONARY TUBERCULOSIS
title_fullStr SURGERY FOR DRUG-RESISTANT DESTRUCTIVE PULMONARY TUBERCULOSIS
title_full_unstemmed SURGERY FOR DRUG-RESISTANT DESTRUCTIVE PULMONARY TUBERCULOSIS
title_short SURGERY FOR DRUG-RESISTANT DESTRUCTIVE PULMONARY TUBERCULOSIS
title_sort surgery for drug resistant destructive pulmonary tuberculosis
topic drug resistance in pathogen
pulmonary tuberculosis
url https://www.tibl-journal.com/jour/article/view/346
work_keys_str_mv AT snskornyakov surgeryfordrugresistantdestructivepulmonarytuberculosis
AT iyamotus surgeryfordrugresistantdestructivepulmonarytuberculosis
AT eikildyusheva surgeryfordrugresistantdestructivepulmonarytuberculosis
AT idmedvinsky surgeryfordrugresistantdestructivepulmonarytuberculosis
AT avbazhenov surgeryfordrugresistantdestructivepulmonarytuberculosis
AT avsavelyev surgeryfordrugresistantdestructivepulmonarytuberculosis