Recent advances in innovative biomaterials for promoting bladder regeneration: processing and functionalization
The bladder is a dynamic organ located in the lower urinary tract, responsible for complex and important physiological activities in the human body, including collecting and storing urine. Severe diseases or bladder injuries often lead to tissue destruction and loss of normal function, requiring sur...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2025-01-01
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| Series: | Frontiers in Bioengineering and Biotechnology |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fbioe.2024.1528658/full |
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| author | Yi Zhang Fu’an Ding Junjie Han Zongliang Wang Wenjie Tian |
| author_facet | Yi Zhang Fu’an Ding Junjie Han Zongliang Wang Wenjie Tian |
| author_sort | Yi Zhang |
| collection | DOAJ |
| description | The bladder is a dynamic organ located in the lower urinary tract, responsible for complex and important physiological activities in the human body, including collecting and storing urine. Severe diseases or bladder injuries often lead to tissue destruction and loss of normal function, requiring surgical intervention and reconstruction. The rapid development of innovative biomaterials has brought revolutionary opportunities for modern urology to overcome the limitations of tissue transplantation. This article first summarized the latest research progress in the processing approaches and functionalization of acellular matrix, hydrogels, nanomaterials, and porous scaffolds in repairing and reconstructing the physiological structure and dynamic function of damaged bladder. Then, we discussed emerging strategies for bladder regeneration and functional recovery, such as cell therapy, organoids, etc. Finally, we outlined the important issues and future development prospects of biomaterials in bladder regeneration to inspire future research directions. By reviewing these innovative biomaterials and technologies, we hope to provide appropriate insights to achieve the ultimate goal of designing and manufacturing artificial bladder substitutes with ideal performance in all aspects. |
| format | Article |
| id | doaj-art-17928b57b71a43e180187f307f1e1810 |
| institution | Kabale University |
| issn | 2296-4185 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Bioengineering and Biotechnology |
| spelling | doaj-art-17928b57b71a43e180187f307f1e18102025-01-06T06:59:12ZengFrontiers Media S.A.Frontiers in Bioengineering and Biotechnology2296-41852025-01-011210.3389/fbioe.2024.15286581528658Recent advances in innovative biomaterials for promoting bladder regeneration: processing and functionalizationYi Zhang0Fu’an Ding1Junjie Han2Zongliang Wang3Wenjie Tian4The Second Hospital of Jilin University, Changchun, ChinaThe Second Hospital of Jilin University, Changchun, ChinaThe Second Hospital of Jilin University, Changchun, ChinaKey Laboratory of Polymer Ecomaterials, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun, ChinaThe Second Hospital of Jilin University, Changchun, ChinaThe bladder is a dynamic organ located in the lower urinary tract, responsible for complex and important physiological activities in the human body, including collecting and storing urine. Severe diseases or bladder injuries often lead to tissue destruction and loss of normal function, requiring surgical intervention and reconstruction. The rapid development of innovative biomaterials has brought revolutionary opportunities for modern urology to overcome the limitations of tissue transplantation. This article first summarized the latest research progress in the processing approaches and functionalization of acellular matrix, hydrogels, nanomaterials, and porous scaffolds in repairing and reconstructing the physiological structure and dynamic function of damaged bladder. Then, we discussed emerging strategies for bladder regeneration and functional recovery, such as cell therapy, organoids, etc. Finally, we outlined the important issues and future development prospects of biomaterials in bladder regeneration to inspire future research directions. By reviewing these innovative biomaterials and technologies, we hope to provide appropriate insights to achieve the ultimate goal of designing and manufacturing artificial bladder substitutes with ideal performance in all aspects.https://www.frontiersin.org/articles/10.3389/fbioe.2024.1528658/fullbiomaterialsnanomaterialsbladder regenerationtissue engineeringstem cells |
| spellingShingle | Yi Zhang Fu’an Ding Junjie Han Zongliang Wang Wenjie Tian Recent advances in innovative biomaterials for promoting bladder regeneration: processing and functionalization Frontiers in Bioengineering and Biotechnology biomaterials nanomaterials bladder regeneration tissue engineering stem cells |
| title | Recent advances in innovative biomaterials for promoting bladder regeneration: processing and functionalization |
| title_full | Recent advances in innovative biomaterials for promoting bladder regeneration: processing and functionalization |
| title_fullStr | Recent advances in innovative biomaterials for promoting bladder regeneration: processing and functionalization |
| title_full_unstemmed | Recent advances in innovative biomaterials for promoting bladder regeneration: processing and functionalization |
| title_short | Recent advances in innovative biomaterials for promoting bladder regeneration: processing and functionalization |
| title_sort | recent advances in innovative biomaterials for promoting bladder regeneration processing and functionalization |
| topic | biomaterials nanomaterials bladder regeneration tissue engineering stem cells |
| url | https://www.frontiersin.org/articles/10.3389/fbioe.2024.1528658/full |
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