Multi-organ frailty is enhanced by periodontitis-induced inflammaging
Abstract Background The incidence of periodontitis is high in older individuals. However, its impact on multi-organ frailty remains unclear. We developed mouse models with varying severity and duration of periodontitis to examine its effects. Methods We generated mouse models with mild and severe pe...
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Main Authors: | Yoshitaka Kase, Satoru Morikawa, Yuji Okano, Tatsuya Hosoi, Takazumi Yasui, Yoko Taki-Miyashita, Mitsutaka Yakabe, Maraku Goto, Kazuyuki Ishihara, Sumito Ogawa, Taneaki Nakagawa, Hideyuki Okano |
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Format: | Article |
Language: | English |
Published: |
BMC
2025-02-01
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Series: | Inflammation and Regeneration |
Subjects: | |
Online Access: | https://doi.org/10.1186/s41232-025-00366-5 |
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