Accelerating cell culture media development using Bayesian optimization-based iterative experimental design

Abstract Optimizing operational conditions for complex biological systems used in life sciences research and biotechnology is an arduous task. Here, we apply a Bayesian Optimization-based iterative framework for experimental design to accelerate cell culture media development for two applications. F...

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Bibliographic Details
Main Authors: Harini Narayanan, Joshua A. Hinckley, Rachel Barry, Brendan Dang, Lenna A. Wolffe, Adel Atari, Yuen-Yi Tseng, J. Christopher Love
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-61113-5
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