Recent Advances in Hydroxyapatite Scaffolds Containing Mesenchymal Stem Cells
Modern day tissue engineering and cellular therapies have gravitated toward using stem cells with scaffolds as a dynamic modality to aid in differentiation and tissue regeneration. Mesenchymal stem cells (MSCs) are one of the most studied stem cells used in combination with scaffolds. These cells di...
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| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2015-01-01
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| Series: | Stem Cells International |
| Online Access: | http://dx.doi.org/10.1155/2015/305217 |
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| _version_ | 1832563826152701952 |
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| author | John Michel Matthew Penna Juan Kochen Herman Cheung |
| author_facet | John Michel Matthew Penna Juan Kochen Herman Cheung |
| author_sort | John Michel |
| collection | DOAJ |
| description | Modern day tissue engineering and cellular therapies have gravitated toward using stem cells with scaffolds as a dynamic modality to aid in differentiation and tissue regeneration. Mesenchymal stem cells (MSCs) are one of the most studied stem cells used in combination with scaffolds. These cells differentiate along the osteogenic lineage when seeded on hydroxyapatite containing scaffolds and can be used as a therapeutic option to regenerate various tissues. In recent years, the combination of hydroxyapatite and natural or synthetic polymers has been studied extensively. Due to the interest in these scaffolds, this review will cover the wide range of hydroxyapatite containing scaffolds used with MSCs for in vitro and in vivo experiments. Further, in order to maintain a progressive scope of the field this review article will only focus on literature utilizing adult human derived MSCs (hMSCs) published in the last three years. |
| format | Article |
| id | doaj-art-1787f388a34e4c9588058be16eff6cfe |
| institution | Kabale University |
| issn | 1687-966X 1687-9678 |
| language | English |
| publishDate | 2015-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Stem Cells International |
| spelling | doaj-art-1787f388a34e4c9588058be16eff6cfe2025-02-03T01:12:20ZengWileyStem Cells International1687-966X1687-96782015-01-01201510.1155/2015/305217305217Recent Advances in Hydroxyapatite Scaffolds Containing Mesenchymal Stem CellsJohn Michel0Matthew Penna1Juan Kochen2Herman Cheung3Department of Biomedical Engineering, College of Engineering, University of Miami, 1251 Memorial Drive, MEA 219A, Coral Gables, FL 33146, USADepartment of Biomedical Engineering, College of Engineering, University of Miami, 1251 Memorial Drive, MEA 219A, Coral Gables, FL 33146, USADepartment of Biomedical Engineering, College of Engineering, University of Miami, 1251 Memorial Drive, MEA 219A, Coral Gables, FL 33146, USADepartment of Biomedical Engineering, College of Engineering, University of Miami, 1251 Memorial Drive, MEA 219A, Coral Gables, FL 33146, USAModern day tissue engineering and cellular therapies have gravitated toward using stem cells with scaffolds as a dynamic modality to aid in differentiation and tissue regeneration. Mesenchymal stem cells (MSCs) are one of the most studied stem cells used in combination with scaffolds. These cells differentiate along the osteogenic lineage when seeded on hydroxyapatite containing scaffolds and can be used as a therapeutic option to regenerate various tissues. In recent years, the combination of hydroxyapatite and natural or synthetic polymers has been studied extensively. Due to the interest in these scaffolds, this review will cover the wide range of hydroxyapatite containing scaffolds used with MSCs for in vitro and in vivo experiments. Further, in order to maintain a progressive scope of the field this review article will only focus on literature utilizing adult human derived MSCs (hMSCs) published in the last three years.http://dx.doi.org/10.1155/2015/305217 |
| spellingShingle | John Michel Matthew Penna Juan Kochen Herman Cheung Recent Advances in Hydroxyapatite Scaffolds Containing Mesenchymal Stem Cells Stem Cells International |
| title | Recent Advances in Hydroxyapatite Scaffolds Containing Mesenchymal Stem Cells |
| title_full | Recent Advances in Hydroxyapatite Scaffolds Containing Mesenchymal Stem Cells |
| title_fullStr | Recent Advances in Hydroxyapatite Scaffolds Containing Mesenchymal Stem Cells |
| title_full_unstemmed | Recent Advances in Hydroxyapatite Scaffolds Containing Mesenchymal Stem Cells |
| title_short | Recent Advances in Hydroxyapatite Scaffolds Containing Mesenchymal Stem Cells |
| title_sort | recent advances in hydroxyapatite scaffolds containing mesenchymal stem cells |
| url | http://dx.doi.org/10.1155/2015/305217 |
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