Three serendipitous pathways in E. coli can bypass a block in pyridoxal‐5′‐phosphate synthesis
Abstract Bacterial genomes encode hundreds to thousands of enzymes, most of which are specialized for particular functions. However, most enzymes have inefficient promiscuous activities, as well, that generally serve no purpose. Promiscuous reactions can be patched together to form multistep metabol...
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| Main Authors: | Juhan Kim, Jamie P Kershner, Yehor Novikov, Richard K Shoemaker, Shelley D Copley |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Springer Nature
2010-11-01
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| Series: | Molecular Systems Biology |
| Subjects: | |
| Online Access: | https://doi.org/10.1038/msb.2010.88 |
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