Subcutaneous Panniculitis-Like T-Cell Lymphoma (SPTL) in a Child with Spontaneous Resolution
Subcutaneous panniculitis-like T-cell lymphomas (SPTLs) α/β are rare in childhood. The present report refers to a case of a 7-year-old male child presenting an extensive skin lesion that began when he was 5 years of age. Two biopsies were evaluated using the CD3, CD4, CD8, CD56, βF1, and TIA markers...
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| Format: | Article |
| Language: | English |
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Wiley
2011-01-01
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| Series: | Case Reports in Oncological Medicine |
| Online Access: | http://dx.doi.org/10.1155/2011/639240 |
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| author | Achiléa L. Bittencourt Maria das Graças Silva Vieira Eny Guimarães Carvalho Celeste Cunha Iguaracyra Araujo |
| author_facet | Achiléa L. Bittencourt Maria das Graças Silva Vieira Eny Guimarães Carvalho Celeste Cunha Iguaracyra Araujo |
| author_sort | Achiléa L. Bittencourt |
| collection | DOAJ |
| description | Subcutaneous panniculitis-like T-cell lymphomas (SPTLs) α/β are rare in childhood. The present report refers to a case of a 7-year-old male child presenting an extensive skin lesion that began when he was 5 years of age. Two biopsies were evaluated using the CD3, CD4, CD8, CD56, βF1, and TIA markers. A dense infiltrate of CD3+, CD4−, CD8+, CD56−, βF1+, and TIA+ pleomorphic lymphocytes was found in the subcutis. The previous biopsy showed cytophagic histiocytic panniculitis with a small focus on CD8+ and βF1+ malignant cells. The lesion regressed spontaneously. This case shows that prognosis may be excellent in SPTL (α/β). On the other hand, it also serves as an alert that a biopsy performed in an area of cytophagic panniculitis may lead to misdiagnosis. |
| format | Article |
| id | doaj-art-1774e91e1d5d4709b974cdbe6da5054e |
| institution | Kabale University |
| issn | 2090-6706 2090-6714 |
| language | English |
| publishDate | 2011-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Oncological Medicine |
| spelling | doaj-art-1774e91e1d5d4709b974cdbe6da5054e2025-08-20T03:54:20ZengWileyCase Reports in Oncological Medicine2090-67062090-67142011-01-01201110.1155/2011/639240639240Subcutaneous Panniculitis-Like T-Cell Lymphoma (SPTL) in a Child with Spontaneous ResolutionAchiléa L. Bittencourt0Maria das Graças Silva Vieira1Eny Guimarães Carvalho2Celeste Cunha3Iguaracyra Araujo4Department of Pathology, Complexo Hospitalar Universitário Prof. Edgard Santos, Federal University of Bahia, Salvador, BA, BrazilDepartment of Pathology, Complexo Hospitalar Universitário Prof. Edgard Santos, Federal University of Bahia, Salvador, BA, BrazilOncology Department, Pediatric Hospital Martagão Gesteira, Liga Baiana Contra a Mortalidade Infantil, Salvador, BA, BrazilOncology Department, Pediatric Hospital Martagão Gesteira, Liga Baiana Contra a Mortalidade Infantil, Salvador, BA, BrazilDepartment of Pathology, Complexo Hospitalar Universitário Prof. Edgard Santos, Federal University of Bahia, Salvador, BA, BrazilSubcutaneous panniculitis-like T-cell lymphomas (SPTLs) α/β are rare in childhood. The present report refers to a case of a 7-year-old male child presenting an extensive skin lesion that began when he was 5 years of age. Two biopsies were evaluated using the CD3, CD4, CD8, CD56, βF1, and TIA markers. A dense infiltrate of CD3+, CD4−, CD8+, CD56−, βF1+, and TIA+ pleomorphic lymphocytes was found in the subcutis. The previous biopsy showed cytophagic histiocytic panniculitis with a small focus on CD8+ and βF1+ malignant cells. The lesion regressed spontaneously. This case shows that prognosis may be excellent in SPTL (α/β). On the other hand, it also serves as an alert that a biopsy performed in an area of cytophagic panniculitis may lead to misdiagnosis.http://dx.doi.org/10.1155/2011/639240 |
| spellingShingle | Achiléa L. Bittencourt Maria das Graças Silva Vieira Eny Guimarães Carvalho Celeste Cunha Iguaracyra Araujo Subcutaneous Panniculitis-Like T-Cell Lymphoma (SPTL) in a Child with Spontaneous Resolution Case Reports in Oncological Medicine |
| title | Subcutaneous Panniculitis-Like T-Cell Lymphoma (SPTL) in a Child with Spontaneous Resolution |
| title_full | Subcutaneous Panniculitis-Like T-Cell Lymphoma (SPTL) in a Child with Spontaneous Resolution |
| title_fullStr | Subcutaneous Panniculitis-Like T-Cell Lymphoma (SPTL) in a Child with Spontaneous Resolution |
| title_full_unstemmed | Subcutaneous Panniculitis-Like T-Cell Lymphoma (SPTL) in a Child with Spontaneous Resolution |
| title_short | Subcutaneous Panniculitis-Like T-Cell Lymphoma (SPTL) in a Child with Spontaneous Resolution |
| title_sort | subcutaneous panniculitis like t cell lymphoma sptl in a child with spontaneous resolution |
| url | http://dx.doi.org/10.1155/2011/639240 |
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