KIR-HLA and maternal-infant HIV-1 transmission in sub-Saharan Africa.

KIR-HLA and maternal-infant HIV-1 transmission in sub-Saharan Africa.

Numerous studies have suggested a role for natural killer (NK) cells in attenuation of HIV-1 disease progression via recognition by killer-cell immunoglobulin-like receptors (KIRs) of specific HLA class I molecules. The role of KIR and HLA class I has not been addressed in the context of maternal-in...

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Bibliographic Details
Main Authors: Maria Paximadis, Gregory Minevich, Robert Winchester, Diana B Schramm, Glenda E Gray, Gayle G Sherman, Ashraf H Coovadia, Louise Kuhn, Caroline T Tiemessen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-02-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0016541
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