Efficacy and Safety of Letrozole in Improving Semen Parameters of Subfertile Men with Moderate-to-Severe Oligoasthenoteratozoospermia: A Placebo-controlled Randomised Trial

Efficacy and Safety of Letrozole in Improving Semen Parameters of Subfertile Men with Moderate-to-Severe Oligoasthenoteratozoospermia: A Placebo-controlled Randomised Trial

Background: Currently lack of consensus regarding the medical treatment of men with Oligoasthenoteratozoospermia (OATS). Letrozole is an aromatase inhibitor and may improve semen quality by stimulating hormone synthesis and spermatogenesis. There is lack of evidence on the efficacy and safety of let...

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Bibliographic Details
Main Authors: Pallavi Ullur, N. S. Kubera, Soliappappan Manikandan, Nivedita Nanda, Sujatha Venkatraman, Anusuya Ram
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2025-01-01
Series:Journal of Human Reproductive Sciences
Subjects:
hormonal parameters
letrozole
oestradiol and t:e ratio
oligoasthenoteratozoospermia
testosterone
Online Access:https://journals.lww.com/10.4103/jhrs.jhrs_160_24
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