The first complete 3D reconstruction and morphofunctional mapping of an insect eye

The structure of compound eyes in arthropods has been the subject of many studies, revealing important biological principles. Until recently, these studies were constrained by the two-dimensional nature of available ultrastructural data. By taking advantage of the novel three-dimensional ultrastruct...

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Main Authors: Anastasia A Makarova, Nicholas J Chua, Anna V Diakova, Inna A Desyatirkina, Pat Gunn, Song Pang, C Shan Xu, Harald F Hess, Dmitri B Chklovskii, Alexey A Polilov
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2025-05-01
Series:eLife
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Online Access:https://elifesciences.org/articles/103247
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author Anastasia A Makarova
Nicholas J Chua
Anna V Diakova
Inna A Desyatirkina
Pat Gunn
Song Pang
C Shan Xu
Harald F Hess
Dmitri B Chklovskii
Alexey A Polilov
author_facet Anastasia A Makarova
Nicholas J Chua
Anna V Diakova
Inna A Desyatirkina
Pat Gunn
Song Pang
C Shan Xu
Harald F Hess
Dmitri B Chklovskii
Alexey A Polilov
author_sort Anastasia A Makarova
collection DOAJ
description The structure of compound eyes in arthropods has been the subject of many studies, revealing important biological principles. Until recently, these studies were constrained by the two-dimensional nature of available ultrastructural data. By taking advantage of the novel three-dimensional ultrastructural dataset obtained using volume electron microscopy, we present the first cellular-level reconstruction of the whole compound eye of an insect, the miniaturized parasitoid wasp Megaphragma viggianii. The compound eye of the female M. viggianii consists of 29 ommatidia and contains 478 cells. Despite the almost anucleate brain, all cells of the compound eye contain nuclei. As in larger insects, the dorsal rim area of the eye in M. viggianii contains ommatidia that are believed to be specialized in polarized light detection as reflected in their corneal and retinal morphology. We report the presence of three ‘ectopic’ photoreceptors. Our results offer new insights into the miniaturization of compound eyes and scaling of sensory organs in general.
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spelling doaj-art-17655cd1c14248a6bd7a575db67f51e82025-08-20T02:13:27ZengeLife Sciences Publications LtdeLife2050-084X2025-05-011410.7554/eLife.103247The first complete 3D reconstruction and morphofunctional mapping of an insect eyeAnastasia A Makarova0https://orcid.org/0000-0001-8855-4128Nicholas J Chua1https://orcid.org/0000-0002-6113-1296Anna V Diakova2Inna A Desyatirkina3Pat Gunn4https://orcid.org/0000-0003-1863-1081Song Pang5https://orcid.org/0000-0002-7231-4151C Shan Xu6https://orcid.org/0000-0002-8564-7836Harald F Hess7https://orcid.org/0000-0003-3000-1533Dmitri B Chklovskii8https://orcid.org/0000-0002-4781-2546Alexey A Polilov9https://orcid.org/0000-0002-6214-3627Department of Entomology, Faculty of Biology, Lomonosov Moscow State University, Moscow, Russian FederationCenter for Computational Neuroscience, Flatiron Institute, New York, United StatesDepartment of Entomology, Faculty of Biology, Lomonosov Moscow State University, Moscow, Russian FederationDepartment of Entomology, Faculty of Biology, Lomonosov Moscow State University, Moscow, Russian FederationCenter for Computational Neuroscience, Flatiron Institute, New York, United StatesJanelia Research Campus, Howard Hughes Medical Institute, Ashburn, United States; Yale School of Medicine, New Haven, United StatesJanelia Research Campus, Howard Hughes Medical Institute, Ashburn, United States; Department of Cellular and Molecular Physiology, Yale School of Medicine, New Haven, United StatesJanelia Research Campus, Howard Hughes Medical Institute, Ashburn, United StatesCenter for Computational Neuroscience, Flatiron Institute, New York, United States; Neuroscience Institute, NYU Langone Medical Center, New York, United StatesDepartment of Entomology, Faculty of Biology, Lomonosov Moscow State University, Moscow, Russian FederationThe structure of compound eyes in arthropods has been the subject of many studies, revealing important biological principles. Until recently, these studies were constrained by the two-dimensional nature of available ultrastructural data. By taking advantage of the novel three-dimensional ultrastructural dataset obtained using volume electron microscopy, we present the first cellular-level reconstruction of the whole compound eye of an insect, the miniaturized parasitoid wasp Megaphragma viggianii. The compound eye of the female M. viggianii consists of 29 ommatidia and contains 478 cells. Despite the almost anucleate brain, all cells of the compound eye contain nuclei. As in larger insects, the dorsal rim area of the eye in M. viggianii contains ommatidia that are believed to be specialized in polarized light detection as reflected in their corneal and retinal morphology. We report the presence of three ‘ectopic’ photoreceptors. Our results offer new insights into the miniaturization of compound eyes and scaling of sensory organs in general.https://elifesciences.org/articles/103247Megaphragma viggianiiTrichogrammatidaeminiaturizationvision
spellingShingle Anastasia A Makarova
Nicholas J Chua
Anna V Diakova
Inna A Desyatirkina
Pat Gunn
Song Pang
C Shan Xu
Harald F Hess
Dmitri B Chklovskii
Alexey A Polilov
The first complete 3D reconstruction and morphofunctional mapping of an insect eye
eLife
Megaphragma viggianii
Trichogrammatidae
miniaturization
vision
title The first complete 3D reconstruction and morphofunctional mapping of an insect eye
title_full The first complete 3D reconstruction and morphofunctional mapping of an insect eye
title_fullStr The first complete 3D reconstruction and morphofunctional mapping of an insect eye
title_full_unstemmed The first complete 3D reconstruction and morphofunctional mapping of an insect eye
title_short The first complete 3D reconstruction and morphofunctional mapping of an insect eye
title_sort first complete 3d reconstruction and morphofunctional mapping of an insect eye
topic Megaphragma viggianii
Trichogrammatidae
miniaturization
vision
url https://elifesciences.org/articles/103247
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