A Study on the Role of Omega Fatty Acids as an Adjuvant Therapy in Treatment of Amblyopia

Aim: To study the role of omega fatty acids as an adjuvant therapy in treatment of amblyopia. Methods: This prospective, randomized, interventional study included thirty two patients aged 5-12 years of age with unilateral amblyopia or bilateral amblyopia. One group (A) of sixteen patients were presc...

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Main Author: Shipra Sharda
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2019-01-01
Series:Delhi Journal of Ophthalmology
Subjects:
Online Access:https://journals.lww.com/10.7869/djo.416
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author Shipra Sharda
author_facet Shipra Sharda
author_sort Shipra Sharda
collection DOAJ
description Aim: To study the role of omega fatty acids as an adjuvant therapy in treatment of amblyopia. Methods: This prospective, randomized, interventional study included thirty two patients aged 5-12 years of age with unilateral amblyopia or bilateral amblyopia. One group (A) of sixteen patients were prescribed occlusion therapy and the other group (B) received 1000 mg per day of omega fatty acids along with occlusion for a period of three months. Follow-up assessments included best corrected visual acuity (BCVA) (both distance and near) and stereoacuity measurements at 1 week and end of three months. Results: The mean age of the patients was 8.68 ± 1.55 years. The mean baseline visual acuity for distance was 0.85 ± 0.071 Log MAR equivalent for Group A and 0.81 ± 0.073 Log MAR eq for Group B. At the end of therapy, the mean visual acuity was 0.48 ± 0.91 Log MAR eq and 0.40 ± 0.20 Log MAR equivalent for Group A and B respectively. There was statistically significant improvement in vision within Group A (p value-0.0008) and Group B (p value-0.0001). When both groups were compared, the results were insignificant (p value-0.373). Conclusion: Omega fatty acids improve visual acuity in patients with amblyopia and maintain improved visual acuity but there is no additional benefit when compared to patching alone. This study encourages further research on this subject.
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spelling doaj-art-1765288c451342e0bcb79e95a97376ff2025-08-20T03:11:57ZengWolters Kluwer Medknow PublicationsDelhi Journal of Ophthalmology0972-02002454-27842019-01-01293384210.7869/djo.416A Study on the Role of Omega Fatty Acids as an Adjuvant Therapy in Treatment of AmblyopiaShipra ShardaAim: To study the role of omega fatty acids as an adjuvant therapy in treatment of amblyopia. Methods: This prospective, randomized, interventional study included thirty two patients aged 5-12 years of age with unilateral amblyopia or bilateral amblyopia. One group (A) of sixteen patients were prescribed occlusion therapy and the other group (B) received 1000 mg per day of omega fatty acids along with occlusion for a period of three months. Follow-up assessments included best corrected visual acuity (BCVA) (both distance and near) and stereoacuity measurements at 1 week and end of three months. Results: The mean age of the patients was 8.68 ± 1.55 years. The mean baseline visual acuity for distance was 0.85 ± 0.071 Log MAR equivalent for Group A and 0.81 ± 0.073 Log MAR eq for Group B. At the end of therapy, the mean visual acuity was 0.48 ± 0.91 Log MAR eq and 0.40 ± 0.20 Log MAR equivalent for Group A and B respectively. There was statistically significant improvement in vision within Group A (p value-0.0008) and Group B (p value-0.0001). When both groups were compared, the results were insignificant (p value-0.373). Conclusion: Omega fatty acids improve visual acuity in patients with amblyopia and maintain improved visual acuity but there is no additional benefit when compared to patching alone. This study encourages further research on this subject.https://journals.lww.com/10.7869/djo.416amblyopianeuroplasticityomega fatty acids
spellingShingle Shipra Sharda
A Study on the Role of Omega Fatty Acids as an Adjuvant Therapy in Treatment of Amblyopia
Delhi Journal of Ophthalmology
amblyopia
neuroplasticity
omega fatty acids
title A Study on the Role of Omega Fatty Acids as an Adjuvant Therapy in Treatment of Amblyopia
title_full A Study on the Role of Omega Fatty Acids as an Adjuvant Therapy in Treatment of Amblyopia
title_fullStr A Study on the Role of Omega Fatty Acids as an Adjuvant Therapy in Treatment of Amblyopia
title_full_unstemmed A Study on the Role of Omega Fatty Acids as an Adjuvant Therapy in Treatment of Amblyopia
title_short A Study on the Role of Omega Fatty Acids as an Adjuvant Therapy in Treatment of Amblyopia
title_sort study on the role of omega fatty acids as an adjuvant therapy in treatment of amblyopia
topic amblyopia
neuroplasticity
omega fatty acids
url https://journals.lww.com/10.7869/djo.416
work_keys_str_mv AT shiprasharda astudyontheroleofomegafattyacidsasanadjuvanttherapyintreatmentofamblyopia
AT shiprasharda studyontheroleofomegafattyacidsasanadjuvanttherapyintreatmentofamblyopia