Natural killer cell in the development and treatment of head and neck squamous cell carcinoma
Head and neck squamous cell carcinoma (HNSCC) is one of the most common malignant tumors in the world. It has a high metastasis rate and a poor prognosis. HNSCC often brings severe facial deformitiesand dysfunctions such as eating and pronunciation to patients. Nature Killer cells (NK cells) are inn...
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| Format: | Article |
| Language: | zho |
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Editorial Office of New Medicine
2021-02-01
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| Series: | Yixue xinzhi zazhi |
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| Online Access: | https://yxxz.whuznhmedj.com/storage/attach/2102/nz7WSOXbrjESaGfOxvKj2J5dEjPGiGlRpjYU63xt.pdf |
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| _version_ | 1850051102903369728 |
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| author | Lu-Ming WANG Shang XIE |
| author_facet | Lu-Ming WANG Shang XIE |
| author_sort | Lu-Ming WANG |
| collection | DOAJ |
| description | Head and neck squamous cell carcinoma (HNSCC) is one of the most common malignant tumors in the world. It has a high metastasis rate and a poor prognosis. HNSCC often brings severe facial deformitiesand dysfunctions such as eating and pronunciation to patients. Nature Killer cells (NK cells) are innate immune system effector cells that directly recognize and kill tumor cells. Studies have shown that NK cells activity are associated with the prognosis of HNSCC, and HNSCC developed with the reduction or inhibition of NK cells. Previous studies believe that natural killer cells can be reactivated to improve the curative effect of HNSCC, showing the potential of natural killer cells. This article reviews the application of natural killer cells in the development and treatment of HNSCC. |
| format | Article |
| id | doaj-art-1762fa2b9db14bf9bfd1600301566998 |
| institution | DOAJ |
| issn | 1004-5511 |
| language | zho |
| publishDate | 2021-02-01 |
| publisher | Editorial Office of New Medicine |
| record_format | Article |
| series | Yixue xinzhi zazhi |
| spelling | doaj-art-1762fa2b9db14bf9bfd16003015669982025-08-20T02:53:16ZzhoEditorial Office of New MedicineYixue xinzhi zazhi1004-55112021-02-01311334110.12173/j.issn.1004-5511.2021.01.056218Natural killer cell in the development and treatment of head and neck squamous cell carcinomaLu-Ming WANGShang XIEHead and neck squamous cell carcinoma (HNSCC) is one of the most common malignant tumors in the world. It has a high metastasis rate and a poor prognosis. HNSCC often brings severe facial deformitiesand dysfunctions such as eating and pronunciation to patients. Nature Killer cells (NK cells) are innate immune system effector cells that directly recognize and kill tumor cells. Studies have shown that NK cells activity are associated with the prognosis of HNSCC, and HNSCC developed with the reduction or inhibition of NK cells. Previous studies believe that natural killer cells can be reactivated to improve the curative effect of HNSCC, showing the potential of natural killer cells. This article reviews the application of natural killer cells in the development and treatment of HNSCC.https://yxxz.whuznhmedj.com/storage/attach/2102/nz7WSOXbrjESaGfOxvKj2J5dEjPGiGlRpjYU63xt.pdfnature killer cells head and neck squamous cell carcinoma immunotherapy |
| spellingShingle | Lu-Ming WANG Shang XIE Natural killer cell in the development and treatment of head and neck squamous cell carcinoma Yixue xinzhi zazhi nature killer cells head and neck squamous cell carcinoma immunotherapy |
| title | Natural killer cell in the development and treatment of head and neck squamous cell carcinoma |
| title_full | Natural killer cell in the development and treatment of head and neck squamous cell carcinoma |
| title_fullStr | Natural killer cell in the development and treatment of head and neck squamous cell carcinoma |
| title_full_unstemmed | Natural killer cell in the development and treatment of head and neck squamous cell carcinoma |
| title_short | Natural killer cell in the development and treatment of head and neck squamous cell carcinoma |
| title_sort | natural killer cell in the development and treatment of head and neck squamous cell carcinoma |
| topic | nature killer cells head and neck squamous cell carcinoma immunotherapy |
| url | https://yxxz.whuznhmedj.com/storage/attach/2102/nz7WSOXbrjESaGfOxvKj2J5dEjPGiGlRpjYU63xt.pdf |
| work_keys_str_mv | AT lumingwang naturalkillercellinthedevelopmentandtreatmentofheadandnecksquamouscellcarcinoma AT shangxie naturalkillercellinthedevelopmentandtreatmentofheadandnecksquamouscellcarcinoma |