Fronto‐Orbital Osteoblastoma With Unilateral Exophthalmos: A Rare Presentation and Review of Diagnostic Challenges
ABSTRACT Osteoblastoma is an uncommon benign bone tumor rarely involving the craniofacial skeleton. Manifestations in the fronto‐orbital region are exceptionally rare. A 19‐year‐old man presented with persistent headache, nausea, vomiting, right eye pain, and longstanding right exophthalmos. Imaging...
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| Format: | Article |
| Language: | English |
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Wiley
2025-01-01
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| Series: | Clinical Case Reports |
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| Online Access: | https://doi.org/10.1002/ccr3.70073 |
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| author | Mohammadhossein Khorraminejad‐Shirazi Ali Nabavizadeh Anita Bojnoordi Dena Firouzabadi Abbas Rakhsha Seyed Ali Hosseini Amirreza Dehghanian |
| author_facet | Mohammadhossein Khorraminejad‐Shirazi Ali Nabavizadeh Anita Bojnoordi Dena Firouzabadi Abbas Rakhsha Seyed Ali Hosseini Amirreza Dehghanian |
| author_sort | Mohammadhossein Khorraminejad‐Shirazi |
| collection | DOAJ |
| description | ABSTRACT Osteoblastoma is an uncommon benign bone tumor rarely involving the craniofacial skeleton. Manifestations in the fronto‐orbital region are exceptionally rare. A 19‐year‐old man presented with persistent headache, nausea, vomiting, right eye pain, and longstanding right exophthalmos. Imaging revealed a heterogeneous enhancing lesion located in the right anterior cranial fossa‐orbital apex junction causing pressure on the orbital roof. Differential diagnoses included fibrous dysplasia and meningioma. The tumor was resected via frontal craniotomy. Definitive diagnosis of osteoblastoma was achieved postoperatively through histopathological examination and IHC studies. Craniofacial osteoblastomas, especially in the fronto‐orbital region, are exceptionally rare and may present radiological features similar to other bone pathologies. Accurate diagnosis hinges on histopathological evaluation. A multidisciplinary approach is pivotal for successful diagnosis and treatment of such challenging cases. |
| format | Article |
| id | doaj-art-175fae7e89bc4d54bcc320814a3cc982 |
| institution | Kabale University |
| issn | 2050-0904 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Clinical Case Reports |
| spelling | doaj-art-175fae7e89bc4d54bcc320814a3cc9822025-01-24T05:08:46ZengWileyClinical Case Reports2050-09042025-01-01131n/an/a10.1002/ccr3.70073Fronto‐Orbital Osteoblastoma With Unilateral Exophthalmos: A Rare Presentation and Review of Diagnostic ChallengesMohammadhossein Khorraminejad‐Shirazi0Ali Nabavizadeh1Anita Bojnoordi2Dena Firouzabadi3Abbas Rakhsha4Seyed Ali Hosseini5Amirreza Dehghanian6Department of Pathology, School of Medicine Jahrom University of Medical Sciences Jahrom IranOtolaryngology Research Center, Department of Otolaryngology Shiraz University of Medical Sciences Shiraz IranDepartment of Pathology, School of Medicine Jahrom University of Medical Sciences Jahrom IranClinical Pharmacy Department, Shiraz School of Pharmacy Shiraz University of Medical Sciences Shiraz IranDepartment of Neurosurgery, School of Medicine Shiraz University of Medical Sciences Shiraz IranDepartment of Neurosurgery, School of Medicine Shiraz University of Medical Sciences Shiraz IranTrauma Research Center Shiraz University of Medical Sciences Shiraz IranABSTRACT Osteoblastoma is an uncommon benign bone tumor rarely involving the craniofacial skeleton. Manifestations in the fronto‐orbital region are exceptionally rare. A 19‐year‐old man presented with persistent headache, nausea, vomiting, right eye pain, and longstanding right exophthalmos. Imaging revealed a heterogeneous enhancing lesion located in the right anterior cranial fossa‐orbital apex junction causing pressure on the orbital roof. Differential diagnoses included fibrous dysplasia and meningioma. The tumor was resected via frontal craniotomy. Definitive diagnosis of osteoblastoma was achieved postoperatively through histopathological examination and IHC studies. Craniofacial osteoblastomas, especially in the fronto‐orbital region, are exceptionally rare and may present radiological features similar to other bone pathologies. Accurate diagnosis hinges on histopathological evaluation. A multidisciplinary approach is pivotal for successful diagnosis and treatment of such challenging cases.https://doi.org/10.1002/ccr3.70073case reportcraniofacialfronto‐orbital regionosteoblastoma |
| spellingShingle | Mohammadhossein Khorraminejad‐Shirazi Ali Nabavizadeh Anita Bojnoordi Dena Firouzabadi Abbas Rakhsha Seyed Ali Hosseini Amirreza Dehghanian Fronto‐Orbital Osteoblastoma With Unilateral Exophthalmos: A Rare Presentation and Review of Diagnostic Challenges Clinical Case Reports case report craniofacial fronto‐orbital region osteoblastoma |
| title | Fronto‐Orbital Osteoblastoma With Unilateral Exophthalmos: A Rare Presentation and Review of Diagnostic Challenges |
| title_full | Fronto‐Orbital Osteoblastoma With Unilateral Exophthalmos: A Rare Presentation and Review of Diagnostic Challenges |
| title_fullStr | Fronto‐Orbital Osteoblastoma With Unilateral Exophthalmos: A Rare Presentation and Review of Diagnostic Challenges |
| title_full_unstemmed | Fronto‐Orbital Osteoblastoma With Unilateral Exophthalmos: A Rare Presentation and Review of Diagnostic Challenges |
| title_short | Fronto‐Orbital Osteoblastoma With Unilateral Exophthalmos: A Rare Presentation and Review of Diagnostic Challenges |
| title_sort | fronto orbital osteoblastoma with unilateral exophthalmos a rare presentation and review of diagnostic challenges |
| topic | case report craniofacial fronto‐orbital region osteoblastoma |
| url | https://doi.org/10.1002/ccr3.70073 |
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