Withdrawal from Long-Term Use of Unusually High-Dose Oxazepam
Benzodiazepine (BZD) misuse is a worldwide problem that healthcare professionals encounter in daily practice. High-dose BZD withdrawal is usually a long process that may require referral to an inpatient rehabilitation unit. Relapses after withdrawal are common. BZD withdrawal can cause complications...
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| Format: | Article |
| Language: | English |
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Wiley
2021-01-01
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| Series: | Case Reports in Psychiatry |
| Online Access: | http://dx.doi.org/10.1155/2021/2140723 |
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| author | Antti Mustonen Juhani Leijala Johanna Aronranta Antero Lassila Mauri Aalto Janne Koskimäki |
| author_facet | Antti Mustonen Juhani Leijala Johanna Aronranta Antero Lassila Mauri Aalto Janne Koskimäki |
| author_sort | Antti Mustonen |
| collection | DOAJ |
| description | Benzodiazepine (BZD) misuse is a worldwide problem that healthcare professionals encounter in daily practice. High-dose BZD withdrawal is usually a long process that may require referral to an inpatient rehabilitation unit. Relapses after withdrawal are common. BZD withdrawal can cause complications including seizures, suicidal behavior, anxiety, and depression. Guidelines describe tapering protocols for modest doses; however, protocols for exceptionally high-dose BZD withdrawal are not well described. Herein, we describe a BZD tapering protocol for a patient with daily use of high-dose (1800 mg) oxazepam (OXP). The BZD tapering was administered in an inpatient psychiatric hospital, and the outcome was evaluated monthly after discharge for three months. This report describes a unique case of high-dose OXP withdrawal and also outlines an optional protocol to apply when clinicians encounter these unusual cases. |
| format | Article |
| id | doaj-art-175f7f4e40c24626992afd360f636256 |
| institution | Kabale University |
| issn | 2090-6838 |
| language | English |
| publishDate | 2021-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Psychiatry |
| spelling | doaj-art-175f7f4e40c24626992afd360f6362562025-02-03T01:28:54ZengWileyCase Reports in Psychiatry2090-68382021-01-01202110.1155/2021/2140723Withdrawal from Long-Term Use of Unusually High-Dose OxazepamAntti Mustonen0Juhani Leijala1Johanna Aronranta2Antero Lassila3Mauri Aalto4Janne Koskimäki5Faculty of Medicine and Health TechnologyDepartment of PsychiatryDepartment of PsychiatryDepartment of PsychiatryFaculty of Medicine and Health TechnologyDepartment of PsychiatryBenzodiazepine (BZD) misuse is a worldwide problem that healthcare professionals encounter in daily practice. High-dose BZD withdrawal is usually a long process that may require referral to an inpatient rehabilitation unit. Relapses after withdrawal are common. BZD withdrawal can cause complications including seizures, suicidal behavior, anxiety, and depression. Guidelines describe tapering protocols for modest doses; however, protocols for exceptionally high-dose BZD withdrawal are not well described. Herein, we describe a BZD tapering protocol for a patient with daily use of high-dose (1800 mg) oxazepam (OXP). The BZD tapering was administered in an inpatient psychiatric hospital, and the outcome was evaluated monthly after discharge for three months. This report describes a unique case of high-dose OXP withdrawal and also outlines an optional protocol to apply when clinicians encounter these unusual cases.http://dx.doi.org/10.1155/2021/2140723 |
| spellingShingle | Antti Mustonen Juhani Leijala Johanna Aronranta Antero Lassila Mauri Aalto Janne Koskimäki Withdrawal from Long-Term Use of Unusually High-Dose Oxazepam Case Reports in Psychiatry |
| title | Withdrawal from Long-Term Use of Unusually High-Dose Oxazepam |
| title_full | Withdrawal from Long-Term Use of Unusually High-Dose Oxazepam |
| title_fullStr | Withdrawal from Long-Term Use of Unusually High-Dose Oxazepam |
| title_full_unstemmed | Withdrawal from Long-Term Use of Unusually High-Dose Oxazepam |
| title_short | Withdrawal from Long-Term Use of Unusually High-Dose Oxazepam |
| title_sort | withdrawal from long term use of unusually high dose oxazepam |
| url | http://dx.doi.org/10.1155/2021/2140723 |
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